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通过有机催化的三组分反应合成吡喃并稠合香豆素的非对映选择性合成。

A diastereoselective synthesis of pyrano fused coumarins via organocatalytic three-component reaction.

机构信息

Shahid Beheshti University, Tehran, Islamic Republic of Iran.

出版信息

Org Biomol Chem. 2013 Jan 14;11(2):279-86. doi: 10.1039/c2ob26203g. Epub 2012 Nov 22.

Abstract

A new method for the synthesis of pyran fused coumarins by 3-bromo-4-hydroxycoumarins as cyclic α-halo ketones based on an organocatalyst assisted three-component tandem reaction is investigated. To the best of our knowledge, cyclic α-halo ketones have not yet been used for the synthesis of pyran fused coumarins.

摘要

研究了一种以 3-溴-4-羟基香豆素为环状α-卤代酮的新型有机催化剂辅助的三组分串联反应合成吡喃并香豆素的方法。据我们所知,环状α-卤代酮尚未用于吡喃并香豆素的合成。

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