Laboratory of Clinical and Translational Studies, National Institutes of Health, National Institute on Alcohol Abuse and Alcoholism, 10 Center Drive, Building 10-CRC Hatfield Center, Room 1-5330, Bethesda, MD 20892-1108, USA.
BMC Med. 2012 Nov 23;10:146. doi: 10.1186/1741-7015-10-146.
Episodes of explosive rage and violence comprise a symptom complex which can have a devastating effect on a person's life. In the community this behavior is seen as workplace violence, domestic abuse and road rage, while in the clinical setting, this behavior is rarely mentioned by patients, despite evidence that it can signify an important biological disorder that may afflict more than three percent of the population.
Patients are often reluctant to seek help for episodic attacks of rage, especially attacks which are accompanied by physical violence. Although, in the past, clinicians have had few treatment options to offer, recent neuroscience advances have created new possibilities to understand and help patients with this neglected problem. No formal medical guidelines for treating violence exist; however, many patients can be helped by diagnosis, referral and treatment. Treatment can include pharmaceuticals and nutrients, as well as referral for anger management or behavioral therapy.
The astute clinician has an opportunity to positively impact an important problem through the diagnosis and treatment of patients with symptoms of intermittent explosive disorder.
爆发性愤怒和暴力事件构成了一种症状综合体,会对一个人的生活造成毁灭性的影响。在社区中,这种行为被视为工作场所暴力、家庭暴力和路怒症,而在临床环境中,尽管有证据表明,这种行为可能代表着一种重要的生物学障碍,可能影响超过 3%的人口,但患者很少提及这种行为。
患者通常不愿意因阵发性愤怒发作寻求帮助,尤其是伴有身体暴力的发作。尽管过去临床医生的治疗选择有限,但最近神经科学的进展为理解和帮助这一被忽视的问题的患者创造了新的可能性。目前尚无针对暴力行为的正式医学指南;然而,许多患者可以通过诊断、转介和治疗得到帮助。治疗可以包括药物和营养物质,以及愤怒管理或行为疗法的转介。
通过对间歇性爆发性障碍患者的诊断和治疗,有洞察力的临床医生有机会积极解决这一重要问题。