Varoglu E, Kaya B, Sari O
Konya University, Meram Medical Faculty, Department of Nuclear Medicine, Konya, Turkey.
Rev Esp Med Nucl Imagen Mol. 2013 Jan;32(1):43-5. doi: 10.1016/j.remn.2012.04.004. Epub 2012 May 30.
It is well known that hematopoietic cytokine stimulation can cause increased fluorodeoxyglucose (FDG) accumulation in bone marrow on PET/CT imaging, which simulates that seen in patients with bone marrow metastases. However, increased bone marrow FDG uptake can be caused by other etiologies. We report a patient with operated renal cell carcinoma had no history of hematopoietic cytokine stimulation. The FDG PET/CT images showed increased bone marrow FDG uptake, and the patient was diagnosed as chronic myeloid leukemia. This case revealed that increased FDG uptake on bone marrow may be related to neoplastic disease of the hematopoietic tissues.
众所周知,造血细胞因子刺激可导致骨髓在PET/CT成像上的氟脱氧葡萄糖(FDG)摄取增加,这与骨髓转移患者的情况相似。然而,骨髓FDG摄取增加也可能由其他病因引起。我们报告1例接受手术治疗的肾细胞癌患者,无造血细胞因子刺激史。FDG PET/CT图像显示骨髓FDG摄取增加,该患者被诊断为慢性髓性白血病。此病例表明,骨髓FDG摄取增加可能与造血组织的肿瘤性疾病有关。