Neurology Unit, Versilia Hospital, via Aurelia, Lido di Camaiore, Lucca, Italy.
Acta Neurol Belg. 2013 Jun;113(2):111-5. doi: 10.1007/s13760-012-0161-7. Epub 2012 Nov 21.
The maintenance of appropriate social behavior is a very complex process with many contributing factors. Social and moral judgments rely on the proper functioning of neural circuits concerned with complex cognitive and emotional processes. Damage to these systems may lead to distinct social behavior abnormalities. When patients present with dysmoral behavior for the first time, as a change from a prior pervasive pattern of behavior, clinicians need to consider a possible, causative brain disorder. The aim is to explore sociopathy as a manifestation of dementia. We searched electronic databases and key journals for original research and review articles on sociopathy in demented patients using the search terms "sociopathy, acquired sociopathy, sociopathic behavior, dementia, and personality". In conclusion, dementia onset may be heralded by changes in personality including alteration in social interpersonal behavior, personal regulation, and empathy. The sociopathy of dementia differs from antisocial/psychopathic personality disorders.
维持适当的社会行为是一个非常复杂的过程，有许多因素会影响。社会和道德判断依赖于与复杂认知和情感过程相关的神经回路的正常运作。这些系统的损伤可能导致明显的社会行为异常。当患者首次出现不道德行为时，即从先前普遍存在的行为模式发生变化，临床医生需要考虑可能存在导致该行为的脑部疾病。目的是探讨痴呆症患者的反社会行为。我们使用“反社会行为、后天性反社会行为、反社会行为、痴呆症和人格”等检索词，在电子数据库和主要期刊中搜索关于痴呆症患者反社会行为的原始研究和综述文章。总之，痴呆症的发病可能以人格改变为先兆，包括社会人际行为、个人调节和同理心的改变。痴呆症的反社会行为不同于反社会/精神病态人格障碍。
