由流行的耐甲氧西林金黄色葡萄球菌-15变种引起的坏死性筋膜炎。
Necrotizing fasciitis caused by a variant of epidemic methicillin resistant Staphylococcus aureus -15.
作者信息
Govindan S, Chakrakodi B, Prabhakara S, Arakere G, Kumar S, Bairy I
机构信息
Department of Microbiology, Melaka Manipal Medical College, Manipal University, Manipal, India.
出版信息
Indian J Med Microbiol. 2012 Oct-Dec;30(4):476-9. doi: 10.4103/0255-0857.103778.
We report a case of necrotizing fasciitis (NF), caused by community-acquired epidemic methicillin resistant Staphylococcus aureus 15 (EMRSA 15). The patient had a prolonged recovery period following treatment with antibiotics and surgical debridement of the infected part. Molecular characterization revealed that the isolate carried Staphylococcal Cassette Chromosome mec (SCC mec) type IV harboring Panton-Valentine Leucocidin (pvl) gene and having accessory gene regulator (agr) type I. The isolate was positive for enterotoxin gene cluster (egc). Pulsed field gel electrophoresis patterns revealed that the isolate belonged sequence type 22, which is an Indian variant of EMRSA 15, reported earlier.
我们报告了一例由社区获得性流行耐甲氧西林金黄色葡萄球菌15型（EMRSA 15）引起的坏死性筋膜炎（NF）病例。该患者在接受抗生素治疗及对感染部位进行手术清创后，恢复期较长。分子特征分析显示，分离株携带IV型葡萄球菌盒式染色体mec（SCC mec），含有杀白细胞素（pvl）基因，且具有I型辅助基因调节因子（agr）。该分离株的肠毒素基因簇（egc）呈阳性。脉冲场凝胶电泳图谱显示，该分离株属于序列型22，这是先前报道的EMRSA 15的印度变种。
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