Department of Dermatology, Roskilde Hospital, Health Sciences Faculty, University of Copenhagen, Roskilde, Denmark.
Dermatology. 2012;225(3):242-7. doi: 10.1159/000343770. Epub 2012 Nov 22.
Optical coherence tomography (OCT) is a non-invasive optical imaging technique providing high-resolution images. OCT may be useful as a monitoring tool during treatment of actinic keratoses (AK) and skin cancer.
To examine and describe how OCT skin morphology changes when the tissue is exposed to the effects of cryotherapy.
Normal ex vivo skin and in vivo AK lesions were examined. Cryotherapy was applied and OCT images were acquired at defined time points. OCT morphology was described.
Cryotherapy treatment produced an opaque iceball, and freezing depth could not be monitored by OCT. Vesicle formation after cryotherapy could be identified in OCT images. In ex vivo skin no vesicle formation occurred.
OCT cannot monitor the freezing depth, but OCT was able to visualise AK lesions and vesicle formation shortly after cryotherapy. Results add to the assumption that OCT could be used in monitoring non-invasive treatments.
光学相干断层扫描（OCT）是一种非侵入性的光学成像技术，可提供高分辨率图像。OCT 可能在光化性角化病（AK）和皮肤癌的治疗过程中作为一种监测工具。
研究并描述 OCT 皮肤形态在组织暴露于冷冻疗法的影响下如何发生变化。
检查离体正常皮肤和体内 AK 病变。施加冷冻疗法，并在规定的时间点获取 OCT 图像。描述 OCT 形态。
冷冻疗法治疗后会产生不透明的冰球，OCT 无法监测到冷冻深度。冷冻疗法后形成的水疱可在 OCT 图像中识别。在离体皮肤中，没有水疱形成。
OCT 无法监测冷冻深度，但 OCT 能够在冷冻疗法后短时间内可视化 AK 病变和水疱形成。这些结果增加了 OCT 可用于监测非侵入性治疗的假设。
Zotero 插件