Dhebri Alhad R, Ahmad Amna, Shah Nigam, Arora Pardeep K
Department of Surgery, Tameside General Hospital, Ashton-under-lyne, UK.
BMJ Case Rep. 2012 Nov 27;2012:bcr2012007237. doi: 10.1136/bcr-2012-007237.
Intracystic papillary carcinoma (IPC) of the breast is a rare malignant tumour, found mainly but not exclusively in elderly women. IPC may be asymptomatic or presents with a palpable mass or blood-stained nipple discharge. The tumour is encysted within a dilated duct with arborisation of the fibrovascular stroma and contains nodules of papillary carcinoma surrounded by a thick fibrous capsule. Frequently excisional biopsy is required for diagnosis. The mainstay of treatment is breast-conserving surgery or mastectomy. Sentinel node biopsy could be considered in invasive cases. Adjuvant radiotherapy (XRT) and/or endocrine therapy is considered in appropriate cases. Prognosis is excellent. We report three such cases of IPC, in elderly women, which were successfully treated.
乳腺囊内乳头状癌(IPC)是一种罕见的恶性肿瘤,主要但并非仅见于老年女性。IPC可能无症状,或表现为可触及的肿块或血性乳头溢液。肿瘤被包裹在扩张的导管内,伴有纤维血管间质分支,并包含被厚纤维包膜包围的乳头状癌结节。通常需要切除活检来确诊。治疗的主要方法是保乳手术或乳房切除术。对于浸润性病例可考虑前哨淋巴结活检。在适当的情况下考虑辅助放疗(XRT)和/或内分泌治疗。预后良好。我们报告了3例老年女性的此类IPC病例,均成功治愈。