用于治疗抵抗性抑郁症的神经调节疗法。
Neuromodulation for treatment-resistant depression.
作者信息
Holtzheimer Paul E, Mayberg Helen S
机构信息
Departments of Psychiatry and Surgery, Dartmouth-Hitchcock Medical Center 5D, One Medical Center Drive, Lebanon NH 03756, USA.
出版信息
F1000 Med Rep. 2012;4:22. doi: 10.3410/M4-22. Epub 2012 Nov 1.
Abstract
Treatment-resistant depression affects at least 1-3% of the US population. This article reviews the current state of focal neuromodulation therapies for treatment-resistant depression, focusing on those treatments published clinical data. These include transcranial magnetic stimulation, transcranial direct current stimulation, magnetic seizure therapy, vagus nerve stimulation, direct cortical stimulation, and deep brain stimulation among others. Of these, only two (transcranial magnetic stimulation and vagus nerve stimulation) currently have US Food and Drug Administration approval for the treatment of depression.
摘要
难治性抑郁症影响着至少1%至3%的美国人口。本文回顾了用于难治性抑郁症的局灶性神经调节疗法的现状，重点关注那些已发表临床数据的治疗方法。这些方法包括经颅磁刺激、经颅直流电刺激、磁休克治疗、迷走神经刺激、直接皮层刺激以及深部脑刺激等。其中，目前只有两种（经颅磁刺激和迷走神经刺激）获得了美国食品药品监督管理局批准用于治疗抑郁症。
相似文献
1
Neuromodulation for treatment-resistant depression.
F1000 Med Rep. 2012;4:22. doi: 10.3410/M4-22. Epub 2012 Nov 1.
2
New neuromodulation techniques for treatment resistant depression.
Int J Psychiatry Clin Pract. 2020 Jun;24(2):106-115. doi: 10.1080/13651501.2020.1728340. Epub 2020 Feb 18.
3
Clinical Usefulness of Therapeutic Neuromodulation for Major Depression: A Systematic Meta-Review of Recent Meta-Analyses.
Psychiatr Clin North Am. 2018 Sep;41(3):485-503. doi: 10.1016/j.psc.2018.04.009. Epub 2018 Jul 17.
4
The Efficacy and Safety of Neuromodulation Treatments in Late-Life Depression.
Curr Treat Options Psychiatry. 2020 Sep;7(3):337-348. doi: 10.1007/s40501-020-00216-w. Epub 2020 Jun 3.
5
Brain stimulation for the treatment of psychiatric disorders.
Curr Opin Psychiatry. 2007 May;20(3):250-4; discussion 247-9. doi: 10.1097/YCO.0b013e3280ad4698.
6
Neuroprotection trek--the next generation: neuromodulation I. Techniques--deep brain stimulation, vagus nerve stimulation, and transcranial magnetic stimulation.
Ann N Y Acad Sci. 2003 May;993:1-13; discussion 48-53. doi: 10.1111/j.1749-6632.2003.tb07506.x.
7
Efficacy of repetitive transcranial magnetic stimulation in treatment-resistant depression: the evidence thus far.
Gen Psychiatr. 2019 Aug 12;32(4):e100074. doi: 10.1136/gpsych-2019-100074. eCollection 2019.
8
Neuropsychologic effects of neuromodulation techniques for treatment-resistant depression: a review.
Brain Stimul. 2011 Jan;4(1):17-27. doi: 10.1016/j.brs.2010.01.005. Epub 2010 Feb 11.
9
A Review of Brain Stimulation Treatments for Late-Life Depression.
Curr Treat Options Psychiatry. 2015 Dec;2(4):413-421. doi: 10.1007/s40501-015-0059-0. Epub 2015 Sep 28.
10
Noninvasive Neuromodulation in Headache: An Update.
Neurol India. 2021 Mar-Apr;69(12 Suppl 1):S183-S193. doi: 10.4103/0028-3886.315998.
引用本文的文献
1
The Rate and Risk Factors of Deep Brain Stimulation-Associated Complications: A Single-Center Experience.
Oper Neurosurg. 2025 Apr 1;28(4):519-527. doi: 10.1227/ons.0000000000001323. Epub 2024 Aug 26.
2
Research on treatment-related aspects of depression from India in the preceding decade (2014-2023): An updated systematic review.
Indian J Psychiatry. 2023 Nov;65(11):1112-1121. doi: 10.4103/indianjpsychiatry.indianjpsychiatry_810_23. Epub 2023 Nov 24.
3
Combinatorial approaches for treating neuropsychiatric social impairment.
Philos Trans R Soc Lond B Biol Sci. 2022 Aug 29;377(1858):20210051. doi: 10.1098/rstb.2021.0051. Epub 2022 Jul 11.
4
Changes in pallidal neural activity following long-term symptom improvement from botulinum toxin treatment in DYT6 dystonia: a case report.
J Med Case Rep. 2022 Jan 9;16(1):15. doi: 10.1186/s13256-021-03215-4.
5
Neuroprotective Effects and Therapeutic Potential of Transcorneal Electrical Stimulation for Depression.
Cells. 2021 Sep 21;10(9):2492. doi: 10.3390/cells10092492.
6
A Decade of Progress in Deep Brain Stimulation of the Subcallosal Cingulate for the Treatment of Depression.
J Clin Med. 2020 Oct 12;9(10):3260. doi: 10.3390/jcm9103260.
7
Individual-specific functional connectivity of the amygdala: A substrate for precision psychiatry.
Proc Natl Acad Sci U S A. 2020 Feb 18;117(7):3808-3818. doi: 10.1073/pnas.1910842117. Epub 2020 Feb 3.
8
The tenacious brain: How the anterior mid-cingulate contributes to achieving goals.
Cortex. 2020 Feb;123:12-29. doi: 10.1016/j.cortex.2019.09.011. Epub 2019 Oct 9.
9
Remote Stimulation of Sciatic Nerve Using Cuff Electrodes and Implanted Diodes.
Micromachines (Basel). 2018 Nov 14;9(11):595. doi: 10.3390/mi9110595.
10
Response rate profiles for major depressive disorder: Characterizing early response and longitudinal nonresponse.
Depress Anxiety. 2018 Oct;35(10):992-1000. doi: 10.1002/da.22832. Epub 2018 Sep 7.
本文引用的文献
1
Long-term efficacy of repeated daily prefrontal transcranial magnetic stimulation (TMS) in treatment-resistant depression.
Depress Anxiety. 2012 Oct;29(10):883-90. doi: 10.1002/da.21967. Epub 2012 Jun 11.
2
Long-term effects of nucleus accumbens deep brain stimulation in treatment-resistant depression: evidence for sustained efficacy.
Neuropsychopharmacology. 2012 Aug;37(9):1975-85. doi: 10.1038/npp.2012.44. Epub 2012 Apr 4.
3
Transcranial direct current stimulation for depression: 3-week, randomised, sham-controlled trial.
Br J Psychiatry. 2012 Jan;200(1):52-9. doi: 10.1192/bjp.bp.111.097634.
4
Subcallosal cingulate deep brain stimulation for treatment-resistant unipolar and bipolar depression.
Arch Gen Psychiatry. 2012 Feb;69(2):150-8. doi: 10.1001/archgenpsychiatry.2011.1456. Epub 2012 Jan 2.
5
A multicenter pilot study of subcallosal cingulate area deep brain stimulation for treatment-resistant depression.
J Neurosurg. 2012 Feb;116(2):315-22. doi: 10.3171/2011.10.JNS102122. Epub 2011 Nov 18.
6
Repetitive transcranial magnetic stimulation versus electroconvulsive therapy for the treatment of major depressive disorder, a randomized controlled clinical trial.
J ECT. 2011 Dec;27(4):310-4. doi: 10.1097/YCT.0b013e318221b31c.
7
Transcranial direct current stimulation in treatment resistant depression: a randomized double-blind, placebo-controlled study.
Brain Stimul. 2012 Jul;5(3):242-251. doi: 10.1016/j.brs.2011.08.005. Epub 2011 Sep 7.
8
Deep brain stimulation of the subcallosal cingulate gyrus: further evidence in treatment-resistant major depression.
Int J Neuropsychopharmacol. 2012 Feb;15(1):121-33. doi: 10.1017/S1461145711001088. Epub 2011 Jul 22.
9
Epidural cortical stimulation of the left dorsolateral prefrontal cortex for refractory major depressive disorder.
Neurosurgery. 2011 Nov;69(5):1015-29; discussion 1029. doi: 10.1227/NEU.0b013e318229cfcd.
10
Safety, tolerability, and effectiveness of high doses of adjunctive daily left prefrontal repetitive transcranial magnetic stimulation for treatment-resistant depression in a clinical setting.
J ECT. 2011 Mar;27(1):18-25. doi: 10.1097/YCT.0b013e3181ce1a8c.
Zotero 插件