Leber hereditary optic neuropathy and oxidative stress.
作者信息
Zhuo Yehong, Luo Hongrong, Zhang Kang
机构信息
State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510275, China.
出版信息
Proc Natl Acad Sci U S A. 2012 Dec 4;109(49):19882-3. doi: 10.1073/pnas.1218953109. Epub 2012 Nov 29.
Abstract
摘要
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本文引用的文献
1
Mouse mtDNA mutant model of Leber hereditary optic neuropathy.Leber 遗传性视神经病变的小鼠 mtDNA 突变模型。
Proc Natl Acad Sci U S A. 2012 Dec 4;109(49):20065-70. doi: 10.1073/pnas.1217113109. Epub 2012 Nov 5.
2
Heteroplasmy of mouse mtDNA is genetically unstable and results in altered behavior and cognition.小鼠线粒体 DNA 的异质性是遗传不稳定的，并导致行为和认知改变。
Cell. 2012 Oct 12;151(2):333-343. doi: 10.1016/j.cell.2012.09.004.
3
Strategies for reducing or preventing the generation of oxidative stress.减少或预防氧化应激产生的策略。
Oxid Med Cell Longev. 2011;2011:194586. doi: 10.1155/2011/194586. Epub 2011 Dec 10.
4
LHON: Mitochondrial Mutations and More.LHON：线粒体突变及其他。
Curr Genomics. 2011 Mar;12(1):44-54. doi: 10.2174/138920211794520150.
5
A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine.代谢性疾病、退行性疾病、衰老及癌症的线粒体范式：进化医学的曙光。
Annu Rev Genet. 2005;39:359-407. doi: 10.1146/annurev.genet.39.110304.095751.
6
Severe impairment of complex I-driven adenosine triphosphate synthesis in leber hereditary optic neuropathy cybrids.莱伯遗传性视神经病变胞质杂种中复合体I驱动的三磷酸腺苷合成的严重受损
Arch Neurol. 2005 May;62(5):730-6. doi: 10.1001/archneur.62.5.730.
7
Leber's hereditary optic neuropathy (LHON) pathogenic mutations induce mitochondrial-dependent apoptotic death in transmitochondrial cells incubated with galactose medium.莱伯遗传性视神经病变（LHON）致病突变在与半乳糖培养基孵育的转线粒体细胞中诱导线粒体依赖性凋亡死亡。
J Biol Chem. 2003 Feb 7;278(6):4145-50. doi: 10.1074/jbc.M210285200. Epub 2002 Nov 21.
8
Respiratory function in cybrid cell lines carrying European mtDNA haplogroups: implications for Leber's hereditary optic neuropathy.携带欧洲线粒体DNA单倍群的细胞杂交株的呼吸功能：对莱伯遗传性视神经病变的影响。
Biochim Biophys Acta. 2002 Oct 9;1588(1):7-14. doi: 10.1016/s0925-4439(02)00097-2.
9
Mouse models for mitochondrial disease.线粒体疾病的小鼠模型。
Am J Med Genet. 2001 Spring;106(1):71-93. doi: 10.1002/ajmg.1393.
10
Functional analysis of lymphoblast and cybrid mitochondria containing the 3460, 11778, or 14484 Leber's hereditary optic neuropathy mitochondrial DNA mutation.含有3460、11778或14484型Leber遗传性视神经病变线粒体DNA突变的淋巴母细胞和胞质杂种线粒体的功能分析。
J Biol Chem. 2000 Dec 22;275(51):39831-6. doi: 10.1074/jbc.M006476200.
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