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动脉瘤样骨囊肿:牙科实践中近期遇到的一例病例报告。

The aneurysmal bone cyst: report of a recent case encountered in dental practice.

作者信息

Buch B

机构信息

Section of Maxillo-Facial and Oral Radiology, Department of Oral Medicine and Periodontology, University of the Witwatersrand, Johannesburg. P.O. Box 3, Wits, 2050, South Africa.

出版信息

SADJ. 2011 Aug;66(7):316, 318.

Abstract

BACKGROUND

A sixteen year-old African male with a large, hard swelling at the left gonial angle, presented at a private dental clinic in January 2009. The swelling felt warm, pulsating and was intermittently symptomatic. The unilocular, expansile lesion seen on a panoramic radiograph was provisionally diagnosed as an aneurysmal bone cyst on the basis of age, symptoms and clinical features. However, ameloblastoma was included in the differential diagnosis.

METHODS

The histological examination of an incisional biopsy specimen revealed multiple blood-filled spaces separated by septa of fibrous tissue containing fibroblasts and multinucleated giant cells, thereby confirming the diagnosis of aneurysmal bone cyst.

RESULTS

Unexpectedly, the patient failed to attend an appointment for curettage of the aneurysmal bone cyst by a maxillofacial surgeon.

CONCLUSIONS

Over the past sixty-eight years, it had been postulated that the origin of the aneurysmal bone cyst was a secondary change in a large variety of pre-existing conditions. Other authors, however, have presented convincing evidence of the aneurysmal bone cyst as a primary lesion. More recently a cytogenetic aetiology for primary aneurysmal bone cysts has been postulated. Many factors in the aetiology of this rare and perplexing condition, however, still remain unclear.

摘要

背景

一名16岁的非洲男性,左下颌角出现一个大的硬性肿胀,于2009年1月就诊于一家私立牙科诊所。该肿胀有温热感、搏动性,且间歇性出现症状。根据全景X线片上所见的单房性、膨胀性病变,结合年龄、症状和临床特征,初步诊断为动脉瘤样骨囊肿。然而,鉴别诊断中也包括成釉细胞瘤。

方法

切开活检标本的组织学检查显示多个充满血液的腔隙,被含有成纤维细胞和多核巨细胞的纤维组织间隔分开,从而确诊为动脉瘤样骨囊肿。

结果

出乎意料的是,患者未按预约接受颌面外科医生对动脉瘤样骨囊肿的刮除治疗。

结论

在过去的68年里,一直有人推测动脉瘤样骨囊肿的起源是多种先前存在疾病的继发性改变。然而,其他作者已经提出了令人信服的证据,证明动脉瘤样骨囊肿是一种原发性病变。最近有人推测原发性动脉瘤样骨囊肿的细胞遗传学病因。然而,这种罕见且令人困惑的疾病病因中的许多因素仍不清楚。

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