Department of Neurosurgery, Southern Medical University, Zhujiang Hospital, 253 Industry Road, 510282 Guangzhou, Guangdong, China.
J Clin Neurosci. 2013 Feb;20(2):244-7. doi: 10.1016/j.jocn.2012.01.053. Epub 2012 Nov 30.
Stent-assisted coil embolization is an endovascular treatment for wide-necked intracranial aneurysms, but the durability of this treatment is not well known. The aim of this study is to investigate the effect of the Neuroform stent (Boston Scientific/Target, Fremont, CA, USA) in progressive occlusion of wide-necked intracranial aneurysms, and to assess any correlation between clinical factors and angiographic follow-up results. The records of 52 patients treated with a Neuroform stent were retrieved for analysis of population characteristics, initial and follow-up angiographic results, and clinical outcomes. Initial angiographic results showed complete occlusion in 21 (40.4%), neck remnants in 22 (42.3%), and residual aneurysms in nine (17.3%). Angiographic follow-up was available in 45 of 52 (86.5%) patients: complete occlusion was achieved in 32 (71.1%), neck remnants were present in eight (17.8%) and residual aneurysms in five (11.1%). Of 31 patients with immediate incomplete obliteration, progressive complete occlusion was achieved in 16 of 28 (57.1%) patients. Clinical follow-up showed good outcomes according to the modified Rankin Scale score. A univariate analysis showed that there was no effect of the tested clinical variables of patient age (p=0.823), gender (p=0.419), aneurysm location (p=0.394), size (p=0.625) and rupture status (p=0.721) on aneurysm occlusion at follow-up. We conclude that the Neuroform stent-assisted neck remodelling technique improves progressive occlusion of wide-necked intracranial aneurysms with good clinical outcomes.
支架辅助弹簧圈栓塞是一种治疗宽颈颅内动脉瘤的血管内治疗方法，但这种治疗的耐久性尚不清楚。本研究旨在探讨 Neuroform 支架（波士顿科学/Target，弗里蒙特，加利福尼亚州，美国）在宽颈颅内动脉瘤进行性闭塞中的作用，并评估临床因素与血管造影随访结果之间的任何相关性。回顾性分析了 52 例接受 Neuroform 支架治疗的患者的记录，以分析人口统计学特征、初始和随访血管造影结果以及临床结果。初始血管造影结果显示完全闭塞 21 例（40.4%），颈部残留 22 例（42.3%），残余动脉瘤 9 例（17.3%）。在 52 例患者中有 45 例（86.5%）进行了血管造影随访：完全闭塞 32 例（71.1%），颈部残留 8 例（17.8%），残余动脉瘤 5 例（11.1%）。在 31 例即时不完全闭塞的患者中，28 例中有 16 例（57.1%）患者进行了渐进性完全闭塞。临床随访显示改良 Rankin 量表评分良好。单因素分析显示，患者年龄（p=0.823）、性别（p=0.419）、动脉瘤位置（p=0.394）、大小（p=0.625）和破裂状态（p=0.721）等测试的临床变量对随访时的动脉瘤闭塞无影响。我们得出结论，Neuroform 支架辅助血管重塑技术可改善宽颈颅内动脉瘤的进行性闭塞，且具有良好的临床效果。
