Department of Neurosurgery, University of Cincinnati (UC) Neuroscience Institute and UC College of Medicine, Cincinnati, OH, USA.
Neuromodulation. 2012 Nov-Dec;15(6):573-9; discussion 579-80. doi: 10.1111/j.1525-1403.2012.00475.x. Epub 2012 Jun 14.
Spinal cord stimulation (SCS) is a valid option for intractable neuropathic pain syndromes, yet some patients cannot undergo the standard awake procedure. Our retrospective study chronicles laminectomy-electrode placement for SCS under general anesthesia and use of compound muscle action potentials (CMAPs) to guide placement in the absence of patient verbal feedback.
After nonsurgical measures proved ineffective for relief of neuropathic pain, 8 men and 11 women underwent SCS lead placement under general rather than local anesthesia because of deafness, language barriers, lidocaine allergy, or extensive scar tissue. A midline thoracic laminectomy was performed, and paddle SCS leads were placed. CMAPs of the rectus abdominis, quadriceps, gastrocnemius, anterior tibialis, abductor hallicus, and intercostal muscles were analyzed. Final lead placement was determined by the right-to-left symmetry of the CMAPs in conjunction with fluoroscopic imaging. Stimulation coverage was evaluated postoperatively.
Inconsistencies were found in lower-extremity CMAPs in the first two procedures. Thereafter, intercostal and rectus abdominis muscle CMAPs obtained in the remaining 17 procedures were consistent, more predictive of final results. Immediately postoperatively, 16 (84.2%) of 19 patients had adequate stimulation coverage and good pain relief with appropriate programming. Of three (15.8%) patients with minimal or no short-term pain relief, lack of response was not attributable to inadequate distribution of stimulation.
With electrophysiologic monitoring and fluoroscopy guidance, placement of SCS laminectomy leads in select patients under general anesthesia may result in appropriate stimulation coverage and pain relief in most.
脊髓刺激(SCS)是治疗难治性神经性疼痛综合征的有效选择,但有些患者无法进行标准的清醒手术。我们的回顾性研究记录了全身麻醉下进行 SCS 椎板切除术-电极放置,并在没有患者口头反馈的情况下使用复合肌肉动作电位(CMAP)来指导放置。
在非手术措施无效缓解神经性疼痛后,由于耳聋、语言障碍、利多卡因过敏或广泛的疤痕组织,8 名男性和 11 名女性在全身麻醉下而不是局部麻醉下接受 SCS 导联放置。进行中线胸椎椎板切除术,并放置桨形 SCS 导联。分析腹直肌、股四头肌、腓肠肌、胫骨前肌、足外侧肌和肋间肌的 CMAP。最终的导联位置通过 CMAP 的左右对称性结合荧光透视成像来确定。术后评估刺激覆盖范围。
在前两次手术中发现下肢 CMAP 存在不一致。此后,在其余 17 次手术中获得的肋间肌和腹直肌 CMAP 是一致的,更能预测最终结果。术后即刻,19 名患者中的 16 名(84.2%)有足够的刺激覆盖范围和良好的疼痛缓解,适当的编程。在 3 名(15.8%)患者中,短期疼痛缓解最小或没有,缺乏反应不是由于刺激分布不足所致。
通过电生理监测和荧光透视引导,在全身麻醉下对选择的患者进行 SCS 椎板切除术导联放置,可能会导致大多数患者获得适当的刺激覆盖范围和疼痛缓解。