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[经阴道胆囊切除术后生活质量评估及妇科随访]

[Assessment of quality of life and gynaecological follow-up after transvaginal cholecystectomy].

作者信息

Hensel M, Schernikau U, Schmidt A, Arlt G

机构信息

Anästhesiologie und Intensivmedizin, Park-Klinik Weißensee, Berlin, Deutschland.

Allgemein- und Viszeralchirurgie, Park-Klinik Weißensee, Berlin, Deutschland.

出版信息

Zentralbl Chir. 2014 Dec;139 Suppl 2:e35-42. doi: 10.1055/s-0032-1315122. Epub 2012 Dec 3.

Abstract

BACKGROUND

It has been reported recently that transvaginal cholecystectomy (TV‑ChE) has advantages over ‘classic’ laparoscopic cholecystectomy (LAP‑ChE) because of its minimal invasiveness. TV‑ChE seems to be associated with a lesser need for analgesics and faster reconvalescence of patients. However, substantial doubts about the transvaginal access and possibly associated complaints and complications of the procedure have been raised. PATIENT/MATERIAL AND METHODS: In this prospective case-control study 30 female patients undergoing transvaginal cholecystectomy (TV‑ChE group) have been compared with 30 women undergoing conventional laparoscopic cholecystectomy (LAP‑ChE group). Female patients were evaluated with special regard to health-related quality of life, outcome data such as surgical complications and gynaecological complaints and changes in sexual behaviour after surgery. Additional attention was given to the extent of postoperative pain, the analgesic consumption and the rate of postoperative nausea and vomiting (PONV).

RESULTS

The demographic data of both groups were comparable to a great extent. Compared to the LAP‑ChE group women of the TV‑ChE group reported less postoperative pain, less PONV and a lower analgesic consumption (p < 0.001). There were no serious complications in the LAP‑ChE group and also none in the TV‑ChE group. In comparison with the preoperative status, the results regarding health-related quality of life and feeling of well-being were significantly better for both groups after a follow-up of 12 months (p < 0.01). However, this effect was especially pronounced in the TV‑ChE group (p < 0.05). No infections of the surgical wound, wound healing problems or other complications were seen in the gynaecological follow-up examination 3 weeks after the TV‑ChE. Two women reported slight and temporary colpotomy-related complaints without any consequences for their sexual behaviour.

CONCLUSIONS

The transvaginal cholecystectomy is a safe and less invasive surgical technique providing for an excellent patient comfort and a fast reconvalescence. TV‑ChE has a positive longterm effect on health-related quality of life. Doubts about transvaginal approach of this surgical technique with regard to an increased risk of infection or late gynaecological complications appear to be unfounded.

摘要

背景

最近有报道称,经阴道胆囊切除术(TV-ChE)因其微创性而优于“传统”腹腔镜胆囊切除术(LAP-ChE)。TV-ChE似乎对镇痛药的需求较少,患者康复更快。然而,对于经阴道入路以及该手术可能相关的不适和并发症存在诸多疑问。

患者/材料与方法:在这项前瞻性病例对照研究中,将30例行经阴道胆囊切除术的女性患者(TV-ChE组)与30例行传统腹腔镜胆囊切除术的女性患者(LAP-ChE组)进行了比较。对女性患者进行了评估,特别关注与健康相关的生活质量、手术并发症和妇科不适等结果数据以及术后性行为的变化。还额外关注了术后疼痛程度、镇痛药使用情况以及术后恶心呕吐(PONV)发生率。

结果

两组的人口统计学数据在很大程度上具有可比性。与LAP-ChE组相比,TV-ChE组女性术后疼痛更少、PONV更少且镇痛药使用量更低(p < 0.001)。LAP-ChE组无严重并发症,TV-ChE组也无严重并发症。与术前状态相比,两组在随访12个月后,与健康相关的生活质量和幸福感结果均显著改善(p < 0.01)。然而,这种效果在TV-ChE组中尤为明显(p < 0.05)。TV-ChE术后3周的妇科随访检查中未发现手术伤口感染、伤口愈合问题或其他并发症。两名女性报告有轻微且短暂的与阴道切开术相关的不适,但对其性行为无任何影响。

结论

经阴道胆囊切除术是一种安全且侵入性较小的手术技术,能为患者提供极佳的舒适度并实现快速康复。TV-ChE对与健康相关的生活质量有积极的长期影响。关于这种手术技术经阴道入路会增加感染风险或晚期妇科并发症的疑虑似乎没有依据。

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