Boylan Center for Cellular and Molecular Physiology, and Davis Center for Regenerative Biology and Medicine, Mount Desert Island Biological Laboratory, PO Box 35, Old Bar Harbor Road, Salisbury Cove, ME 04672, USA.
Curr Biol. 2012 Dec 4;22(23):R1000-1. doi: 10.1016/j.cub.2012.10.024.
Pacemaker cells are specialized cell types that drive biological rhythms like the heartbeat and intestinal peristalsis. What determines whether a cell functions as a pacemaker? Studies in Caenorhabditis elegans suggest that pacemaking activity may be controlled in part by microRNAs.
起搏器细胞是一种特殊的细胞类型,可驱动像心跳和肠道蠕动这样的生物节律。那么,是什么决定了一个细胞是否能充当起搏器呢?秀丽隐杆线虫的研究表明,起搏活动可能部分受 microRNAs 控制。