透明质酸与烷基三甲基铵表面活性剂的梳状离子缔合物。

Comb-like ionic complexes of hyaluronic acid with alkyltrimethylammonium surfactants.

机构信息

Department d'Enginyeria Química, Universitat Politècnica de Catalunya, ETSEIB, Diagonal 647, Barcelona 08028, Spain.

出版信息

Carbohydr Polym. 2013 Jan 30;92(1):691-6. doi: 10.1016/j.carbpol.2012.09.042. Epub 2012 Sep 28.

DOI:10.1016/j.carbpol.2012.09.042

Abstract

Stoichiometric complexes of hyaluronic acid with alkyltrimethylammonium surfactants bearing octadecyl, eicosyl and docosyl groups were prepared by ionic coupling in aqueous solution. The complexes were non soluble in water but soluble in organic solvents. In the solid state they self-assembled in a biphasic layered structure with the alkyl side chains forming a separate phase that melted in the 50-60 °C range. They were stable to heating up to above 200 °C.

摘要

具有十八烷基、二十烷基和二十二烷基的烷基三甲基铵表面活性剂与透明质酸的化学计量复合物通过离子偶联在水溶液中制备。复合物不溶于水但溶于有机溶剂。在固态下，它们自组装成双相层状结构，烷基侧链形成单独的相，在 50-60°C 的范围内熔化。它们在加热到 200°C 以上时仍稳定。