Jarwani Bhavesh S, Motiani Puja, Divetia Ruchir, Thakkar Gurudutta
Department of Emergency Medicine, VSGH, Ahmedabad, Gujarat, India.
J Emerg Trauma Shock. 2012 Oct;5(4):356-9. doi: 10.4103/0974-2700.102413.
Methanol poisoning is a rare but extremely hazardous form of intoxication, generally occurring after suicidal or accidental events. Methanol is a cheap and potent adulterant of illicit liquors. In India, we have witnessed number of mass emergencies due to adulterated alcohol consumption. Although Gujarat State had banned alcohol consumption since 1961, worse hooch tragedies have often taken place. The most severe consequences of methanol intoxication are blindness, a profound metabolic acidosis and various forms of neurological impairment; which occur characteristically after a latent period of several hours or days after ingestion. We present a unique case of acute methanol intoxication presented with, apart from metabolic acidosis and optic neuritis, involvement of central nervous system and peripheral nervous system. He had bilateral optic neuritis, delayed onset polyneuropathy with axonopathy, and radiculopathy. Magnetic resonance imaging findings were consistent with bilateral putaminal necrosis.
甲醇中毒是一种罕见但极其危险的中毒形式,通常发生在自杀或意外事件之后。甲醇是非法酒类中一种廉价且强效的掺假物质。在印度,我们目睹了因饮用掺假酒精而引发的多起大规模紧急事件。尽管古吉拉特邦自1961年起就禁止饮酒,但更严重的私酿酒悲剧却屡屡发生。甲醇中毒最严重的后果是失明、严重的代谢性酸中毒以及各种形式的神经功能损害;这些后果通常在摄入后数小时或数天的潜伏期后出现。我们报告了一例独特的急性甲醇中毒病例,除代谢性酸中毒和视神经炎外,还累及中枢神经系统和周围神经系统。患者患有双侧视神经炎、迟发性轴索性多发性神经病和神经根病。磁共振成像结果与双侧豆状核坏死一致。