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心脏复律除颤器植入术中除颤阈值测试及术后长期疗效

Intraoperative defibrillation threshold testing and postoperative long-term efficacy of cardioverter-defibrillator implantation.

作者信息

Gan Tianyi, Cao Xiaozhi, Yu Zhang, Tang Baopeng, Li Jinxin, Xu Guojun, Zhou Xianhui, Zhang Yanyi, Li Yaodong, Zhang Jianghua

机构信息

Department of Cardiology, First Affiliated Hospital, Xinjiang Medical University, Urumqi, Xinjiang 830054;

出版信息

Exp Ther Med. 2013 Jan;5(1):323-327. doi: 10.3892/etm.2012.797. Epub 2012 Nov 5.

Abstract

The aim of this study was to determine the defibrillation threshold (DFT) of implantable cardioverter-defibrillators (ICDs) and outcomes of treatment. Sixty-four patients received cardioverter-defibrillator implantation. During implantation, the DFT was determined by the defibrillation safety margin (DSM). All patients were followed up for 12-48 months after the implantation. The overall DFT was 14.27±2.56 J and the DSM was 18.40±1.89 J. Malignant ventricular arrhythmias occurred in 42 patients following cardioverter-defibrillator implantation including 500 episodes of non-sustained ventricular tachycardia (VT) and 289 episodes of persistent VT. VT was treated using antitachycardia pacing (ATP); 265 episodes were treated successfully by a single ATP treatment (91.69%) and 12 episodes were treated successfully by two ATP treatments (4.15%). Twelve episodes were converted by low-energy electrical cardioversion (4.15%). A total of 175 ventricular fibrillation (VF) episodes were identified, of which 18 episodes automatically terminated prior to treatment. In total, 146 episodes were converted by a single cardioversion with a defibrillation energy of 13.21±2.58 J and 11 episodes were converted by two cardioversions with a defibrillation energy of 16.19±2.48 J. It is safe and feasible to determine the DFT by DSM measurement during cardioverterdefibrillator implantation.

摘要

本研究的目的是确定植入式心脏复律除颤器(ICD)的除颤阈值(DFT)及治疗效果。64例患者接受了心脏复律除颤器植入。植入过程中,通过除颤安全 margin(DSM)确定DFT。所有患者在植入后随访12至48个月。总体DFT为14.27±2.56 J,DSM为18.40±1.89 J。42例患者在心脏复律除颤器植入后发生恶性室性心律失常,包括500次非持续性室性心动过速(VT)发作和289次持续性VT发作。VT采用抗心动过速起搏(ATP)治疗;265次发作通过单次ATP治疗成功(91.69%),12次发作通过两次ATP治疗成功(4.15%)。12次发作通过低能量电复律转复(4.15%)。共识别出175次心室颤动(VF)发作,其中18次发作在治疗前自动终止。总共146次发作通过单次除颤能量为13.21±2.58 J的复律转复,11次发作通过两次除颤能量为16.19±2.48 J的复律转复。在心脏复律除颤器植入期间通过DSM测量确定DFT是安全可行的。

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