Moritomo H, Nagahata Y, Urakawa T, Takeda K, Hashimoto Y, Ichihara T, Saitoh Y
First Department of Surgery, Kobe University School of Medicine, Japan.
Nihon Geka Gakkai Zasshi. 1990 Feb;91(2):206-13.
We treated 448 patients for peptic ulcer from 1970 to 1988. Among them, 52 cases were bleeding peptic ulcer in the elderly. 32 cases (61.6%) had a duration of illness of less than 3 months, and the most common symptom was abdominal pain (51.9%). 22 cases (44.0%) were in shock and 32 cases (62.7%) had accessory diseases. Twelve cases were treated medically, while 40 cases were treated surgically. Elective operations were performed in 15 cases, and their mortality was 6.7%. Emergent operations were performed in 25 cases, and their mortality was 28.0%. The mortality of of cases involving both shock and accessory diseases was 57.1%, and of this group, all 3 cases treated medically died. When bleeding exceeded 2000cc was the mortality 46.7%. Regarding cases of emergent operation involving shock or accessory diseases, the mortality was 18.2% in the cases treated medically for less than 4 days and had the episodes of massive bleeding less than 3 times, but 62.5% in other cases. The results of this study suggest that aggressive surgical treatment in an early stage may reduce the mortality in elderly patients with peptic ulcer.
1970年至1988年期间,我们共治疗了448例消化性溃疡患者。其中,52例为老年消化性溃疡出血患者。32例(61.6%)病程少于3个月,最常见症状为腹痛(51.9%)。22例(44.0%)出现休克,32例(62.7%)有合并症。12例接受内科治疗,40例接受外科治疗。15例行择期手术,死亡率为6.7%。25例行急诊手术,死亡率为28.0%。合并休克和合并症患者的死亡率为57.1%,该组中所有3例接受内科治疗的患者均死亡。出血超过2000cc时死亡率为46.7%。对于合并休克或合并症的急诊手术患者,内科治疗时间少于4天且大出血次数少于3次的患者死亡率为18.2%,其他患者为62.5%。本研究结果表明,早期积极的手术治疗可能降低老年消化性溃疡患者的死亡率。