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Effects of familial mutations on the monomer structure of Aβ₄₂.
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Structural heterogeneity in familial Alzheimer's disease mutants of amyloid-beta peptides.
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4
Changes to the structure and dynamics in mutations of Aβ(21-30) caused by ions in solution.
J Phys Chem B. 2013 Dec 5;117(48):14907-15. doi: 10.1021/jp408579v. Epub 2013 Nov 21.
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Familial Alzheimer's Disease-Related Mutations Differentially Alter Stability of Amyloid-Beta Aggregates.
J Phys Chem Lett. 2023 Feb 16;14(6):1427-1435. doi: 10.1021/acs.jpclett.2c03729. Epub 2023 Feb 3.
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Role of the familial Dutch mutation E22Q in the folding and aggregation of the 15-28 fragment of the Alzheimer amyloid-beta protein.
Proc Natl Acad Sci U S A. 2008 Apr 22;105(16):6027-32. doi: 10.1073/pnas.0708193105. Epub 2008 Apr 11.
10
The Arctic mutation alters helix length and type in the 11-28 beta-amyloid peptide monomer-CD, NMR and MD studies in an SDS micelle.
J Struct Biol. 2008 Nov;164(2):199-209. doi: 10.1016/j.jsb.2008.07.010. Epub 2008 Aug 14.

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Survey of the Aβ-peptide structural diversity: molecular dynamics approaches.
Biophys Rev. 2024 Nov 20;16(6):701-722. doi: 10.1007/s12551-024-01253-y. eCollection 2024 Dec.
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Computational Study of Amyloidβ Familial Mutations and Metal Interaction: Impact on Monomers and Aggregates Dynamical Behaviors.
Inorg Chem. 2024 Mar 11;63(10):4725-4737. doi: 10.1021/acs.inorgchem.3c04555. Epub 2024 Feb 26.
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Folding@home: Achievements from over 20 years of citizen science herald the exascale era.
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Pulsed Hydrogen-Deuterium Exchange Reveals Altered Structures and Mechanisms in the Aggregation of Familial Alzheimer's Disease Mutants.
ACS Chem Neurosci. 2021 Jun 2;12(11):1972-1982. doi: 10.1021/acschemneuro.1c00072. Epub 2021 May 14.
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Emergence of Barrel Motif in Amyloid-β Trimer: A Computational Study.
J Phys Chem B. 2020 Nov 25;124(47):10617-10631. doi: 10.1021/acs.jpcb.0c05508. Epub 2020 Nov 12.

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Distinct Morphologies for Amyloid Beta Protein Monomer: Aβ1-40, Aβ1-42, and Aβ1-40(D23N).
J Chem Theory Comput. 2011 Aug 9;7(8):2584-92. doi: 10.1021/ct1006967. Epub 2011 Jun 29.
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Antiparallel β-sheet architecture in Iowa-mutant β-amyloid fibrils.
Proc Natl Acad Sci U S A. 2012 Mar 20;109(12):4443-8. doi: 10.1073/pnas.1111305109. Epub 2012 Mar 8.
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Homogeneous and heterogeneous tertiary structure ensembles of amyloid-β peptides.
Biochemistry. 2011 Sep 6;50(35):7612-28. doi: 10.1021/bi200732x. Epub 2011 Aug 15.
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Characterizing the structural behavior of selected Aβ-42 monomers with different solubilities.
J Phys Chem B. 2011 May 5;115(17):4900-10. doi: 10.1021/jp1086575. Epub 2011 Apr 12.
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Everything you wanted to know about Markov State Models but were afraid to ask.
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Elucidation of amyloid beta-protein oligomerization mechanisms: discrete molecular dynamics study.
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A role for helical intermediates in amyloid formation by natively unfolded polypeptides?
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