HIV 感染者内固定后骨折愈合。
Fracture union following internal fixation in the HIV population.
机构信息
Beit-CURE International Hospital, Blantyre, Malawi.
出版信息
Injury. 2013 Jun;44(6):830-3. doi: 10.1016/j.injury.2012.11.024. Epub 2012 Dec 23.
INTRODUCTION
HIV is thought to be associated with increased rates of fracture non-union. We report on a prospective cohort of 96 HIV positive patients with 107 fractures that required internal fixation. The CD4 count was measured and patients were reviewed until eventual clinical or radiological union or non-union was established.
RESULTS
Four percent of fractures (4 out of 100) failed to unite. Three patients required one further procedure to induce union, and two developed avascular necrosis. The CD4 count was not related to fracture union.
CONCLUSION
Contrary to previous assumptions, this study suggests that HIV infection does not increase rates of non-union in surgically managed fractures.
引言
人们认为 HIV 与更高的骨折不愈合率有关。我们报告了一项前瞻性队列研究，共纳入 96 例 HIV 阳性患者，共 107 处需要内固定的骨折。测量了 CD4 计数，并对患者进行了随访，直到最终临床或影像学上的愈合或不愈合确定。
结果
4%的骨折（4/100）未愈合。3 名患者需要进一步的手术来促进愈合，2 名患者发生了骨坏死。CD4 计数与骨折愈合无关。
结论
与之前的假设相反，本研究表明，HIV 感染不会增加手术治疗骨折的不愈合率。
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