Serra Héctor A, Fadel Daniel O
Carrera de Médico Especialista en Farmacología, Facultad de Medicina, UBA.
Vertex. 2012 Sep-Oct;23(105):339-49.
Nowadays, the term receptor is obvious in psychopharmacology. However, this was not so obvious a century ago. To try to explain how drugs act, European scientists began to develop theories that turned into deeds with the scientific progress. Thus, the receptor concept and their applications in medicine and psychiatry began to gain substance. In this paper we relate the facts that have led to the current knowledge of receptor, the cornerstone of pharmacology.
如今,“受体”一词在精神药理学中已十分常见。然而,在一个世纪前,情况并非如此。为了解释药物的作用机制,欧洲科学家们开始提出各种理论,随着科学的进步,这些理论逐渐得到实践验证。于是,受体概念及其在医学和精神病学中的应用开始变得充实起来。在本文中,我们将阐述促成目前对受体这一药理学基石的认识的相关事实。