Corciovă C, Turnea M, Matei Daniela, Andritoi D
University of Medicine and Pharmacy, Grigore T. Popa-Iaşi School of Medical Bioengineering.
Rev Med Chir Soc Med Nat Iasi. 2012 Jul-Sep;116(3):927-32.
Impedance plethysmography is a method for determining changes in body tissue volumes, based on the measurement of electric impedance at the body surface. Because it is a non-invasive and cost-effective method to measure and analyze hemodynamics, it would bring to physiologists very important diagnostic information for the continuous care of critical patients with hemodynamic disorders.
This study aimed at acquiring non-invasively and at analyzing plethysmografic waves by measuring the electrical impedance. For measurements we built a device that was designed as an injection module with a microcontroller, a programmable waveform generator, and a voltage controlled current source which generates a sinusoidal pulse with adjustable frequency (10-200 kHz) and adjustable intensity. In output, the device delivers an analogical signal representing the variation of the impedance of the explored section. The acquisition of the bioimpedance signal on PC was made easier by the use of a national instrument data acquisition device, the NI USB 6009.
The bioimpedance signal processing, the user interface and the display were managed by MATLAB. Sample impedance data for a test subject are presented. From the experimental results, it is shown that the proposed bioimpedance measuring system could provide good performance over the frequency range for central or peripheral territory.
The clinical importance of these findings is that this method can measure vascular parameters noninvasively, continuously and more conveniently in humans.
阻抗体积描记法是一种基于体表电阻抗测量来确定身体组织体积变化的方法。由于它是一种测量和分析血流动力学的非侵入性且经济高效的方法,它能为生理学家提供非常重要的诊断信息,用于对患有血流动力学紊乱的重症患者进行持续护理。
本研究旨在通过测量电阻抗来无创获取并分析体积描记波。为了进行测量,我们构建了一个设备,该设备设计为一个带有微控制器、可编程波形发生器和压控电流源的注射模块,该电流源可产生频率(10 - 200 kHz)和强度可调的正弦脉冲。在输出时,该设备会输出一个表示被探测部位阻抗变化的模拟信号。使用国家仪器数据采集设备NI USB 6009使在个人计算机上采集生物阻抗信号变得更加容易。
生物阻抗信号处理、用户界面和显示由MATLAB管理。展示了一名测试对象的样本阻抗数据。从实验结果可以看出,所提出的生物阻抗测量系统在中心或外周区域的频率范围内能够提供良好的性能。
这些发现的临床重要性在于,这种方法可以在人体中无创、连续且更方便地测量血管参数。