Am J Gastroenterol. 2013 Jan;108(1):140-2. doi: 10.1038/ajg.2012.384.
Excess body fat is widely considered one of the factors that is linked to acute pancreatitis (AP), but its specific role is far from being fully understood. This Editorial offers an insight into the recent research in this field with particular emphasis on findings of the latest prospective population-based studies. It discusses whether body fat distribution influences the risk of developing first-time AP, whether excess body fat affects clinically meaningful outcomes in patients with developed AP, and whether a case can be made for biological interaction between several metabolic components in this disease.
过多的体脂肪被广泛认为是与急性胰腺炎(AP)相关的因素之一,但它的具体作用还远未被充分理解。这篇社论深入探讨了该领域的最新研究,特别强调了最新的基于人群的前瞻性研究结果。它讨论了体脂肪分布是否会影响首次发生 AP 的风险,过多的体脂肪是否会影响已发生 AP 患者的临床有意义的结局,以及在这种疾病中,几种代谢成分之间是否存在生物学相互作用的情况。