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缩短静脉输注时间对降低胃癌根治术后导管相关血流感染的影响

Effect of shorter term of intravenous infusion for reduction of catheter-related bloodstream infection after gastrectomy.

作者信息

Kawamura Hideki, Tanioka Toshiro, Kuji Mariko, Shibuya Kazuaki, Takahashi Masahiro

机构信息

Department of Surgery, JA Sapporo Kosei Hospital, Sapporo, Japan.

出版信息

Int Surg. 2012 Oct-Dec;97(4):345-50. doi: 10.9738/CC147.1.

Abstract

After gastrectomy, a longer period of intravenous alimentation is required than for other digestive surgeries, portending a higher risk of catheter-related bloodstream infection (CRBSI). From assessment of CRBSI occurring between 2004 and 2007 (preintervention group), the duration of intravenous infusion between 2008 and 2010 (postintervention group) was changed to shorter-term (6-day) infusion. To verify the effect of changes in injection schedule on the incidence of CRBSI, the occurrence of CRBSI was studied comparatively among preintervention and postintervention cases, excluding cases requiring intravenous infusion preoperatively, and cases requiring long-term intravenous infusion postoperatively due to postoperative complications. The rate of CRBSI in the postintervention group (0%; 0 of 298) was significantly lower than that in the preintervention group (1.7%; 8 of 477; P = 0.026). There was no significant difference between preintervention and postintervention groups in postoperative complications. Six-day infusion decreased the incidence of CRBSI after gastrectomy significantly, without increasing postoperative complications.

摘要

胃切除术后,与其他消化手术相比,需要更长时间的静脉营养支持,这意味着导管相关血流感染(CRBSI)的风险更高。通过评估2004年至2007年期间发生的CRBSI(干预前组),将2008年至2010年期间(干预后组)的静脉输液时间改为短期(6天)输液。为了验证注射方案的改变对CRBSI发生率的影响,对干预前和干预后的病例进行了比较研究,排除术前需要静脉输液的病例以及术后因并发症需要长期静脉输液的病例。干预后组的CRBSI发生率(0%;298例中0例)显著低于干预前组(1.7%;477例中8例;P = 0.026)。干预前组和干预后组在术后并发症方面无显著差异。6天输液显著降低了胃切除术后CRBSI的发生率,且未增加术后并发症。

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