VA Palo Alto Health Care System, Stanford University School of Medicine, United States; University of Colorado at Colorado Springs, United States.
J Anxiety Disord. 2013 Aug;27(6):567-75. doi: 10.1016/j.janxdis.2012.10.010. Epub 2012 Nov 6.
This study assessed the degree to which anxiety and depression symptoms are associated with memory and executive functioning among community-dwelling older adults (N=120; M age=74.9 years, SD=7.2 years; 62% women). Participants completed the Geriatric Anxiety Scale, Geriatric Depression Scale, Comorbidity Index, California Verbal Learning Test, Second Edition (CVLT-II), and the Trail Making, Verbal Fluency, and 20 Questions subtests of the Delis-Kaplan Executive Function System (D-KEFS). Multiple regression analyses indicated that anxiety and depression predicted poorer ability to learn new information (CVLT-II, Trials 1-5). Both anxiety and depression predicted performance on the D-KEFS Trail Making test, Number-Letter Switching condition. Anxiety, but not depression, predicted decreased categorization as measured by the D-KEFS 20 Questions, Initial Abstraction Score. Depression but not anxiety, predicted performance on D-KEFS Letter Fluency and Category Fluency. Findings suggest that anxiety and depression have unique relationships with cognitive functioning in community-dwelling older adults.
本研究评估了社区居住的老年成年人(N=120;平均年龄=74.9 岁,标准差=7.2 岁;62%为女性)中焦虑和抑郁症状与记忆和执行功能的关联程度。参与者完成了老年焦虑量表、老年抑郁量表、合并症指数、加利福尼亚语言学习测试第二版(CVLT-II)以及德里斯科尔-卡普兰执行功能系统(D-KEFS)的连线测试、词语流畅性和 20 个问题子测验。多元回归分析表明,焦虑和抑郁预测了学习新信息(CVLT-II,第 1-5 次试验)的能力较差。焦虑和抑郁均预测了 D-KEFS 连线测试,数字-字母转换条件下的表现。焦虑,但不是抑郁,预测了 D-KEFS 20 个问题初始抽象评分中分类能力的下降。抑郁,而不是焦虑,预测了 D-KEFS 字母流畅性和类别流畅性的表现。研究结果表明,焦虑和抑郁与社区居住的老年成年人的认知功能有独特的关系。