Qiu Yong, Sun Xu, Wang Bin, Ding Qi, Zhu Ze-zhang, Qian Bang-ping, Yu Yang, Zhu Feng, Ma Wei-wei
Department of Spine Surgery, Nanjing University, Nanjing, China.
Zhonghua Wai Ke Za Zhi. 2012 Oct;50(10):883-8.
To investigate the early outcome of vertical expandable prosthetic titanium rib (VEPTR) technique in treating early-onset scoliosis.
This study recruited 11 early-onset scoliosis patients (8 boys and 3 girls) who received VEPTR treatment from December 2006 to July 2011 with a minimum follow-up of 12 months. The average age at initial surgery was (7 ± 3) years (range, 3.1 to 9.8 years). VEPTR device, either rib to rib or rib to lumbar, was implanted at initial surgery. During the regular post-operative follow-ups, expansion surgeries were scheduled at an interval of 6 to 12 months. Measurements of primary curve magnitude, apical vertebral translation, thoracic height and T(1)-S(1) height were performed on radiographs, and were compared between those of preoperatively, postoperatively, and at latest follow-up through paired-t tests.
All patients had a mean follow-up of (32 ± 11) months. Totally 41 surgeries were performed, averagely 3.7 surgeries per patient; and 30 expansion surgeries were carried out, averagely 2.7 surgeries per patient. The average interval for each expansion surgery was 8 months. From preoperatively to latest follow-up, the Cobb angle of primary curves was averagely corrected from 78° ± 18° to 55° ± 11° (t = 4.931, P < 0.05), and apical vertebral translation and thoracic kyphosis displayed slight improvement. Average thoracic height increased from (13.3 ± 2.0) cm to (17.2 ± 2.4) cm (t = 8.365, P < 0.001), and average T(1)-S(1) height from (24.4 ± 3.8) cm to (32.5 ± 5.3) cm (t = 9.080, P < 0.001). After initial surgery with VEPTR instrumented, gains in thoracic height and T(1)-S(1) height per expansion surgery averaged (0.8 ± 0.3) cm and (1.8 ± 0.4) cm, respectively. Eight complications occurred in 6 patients, including rib cradle dislodgements, displayed infection, intraoperative pleura rupture and loosening of lumbar pedicle screws.
VEPTR technique proves to be an effective way of preventing curve progression in early-onset scoliosis patients while allowing growth of spine and chest. Yet, indications for such a technique need to be strictly selected because of the relatively high complication rate.
探讨垂直可扩展人工钛肋骨(VEPTR)技术治疗早发性脊柱侧弯的早期疗效。
本研究纳入了2006年12月至2011年7月期间接受VEPTR治疗的11例早发性脊柱侧弯患者(8例男性,3例女性),最小随访时间为12个月。初次手术时的平均年龄为(7±3)岁(范围3.1至9.8岁)。初次手术时植入VEPTR装置,可采用肋骨对肋骨或肋骨对腰椎的方式。在术后定期随访期间,每隔6至12个月安排一次撑开手术。通过X线片测量主弯角度、顶椎平移、胸廓高度和T1-S1高度,并通过配对t检验比较术前、术后及末次随访时的测量结果。
所有患者的平均随访时间为(32±11)个月。共进行了41次手术,平均每位患者3.7次;其中30次为撑开手术,平均每位患者2.7次。每次撑开手术的平均间隔时间为8个月。从术前到末次随访,主弯的Cobb角平均从78°±18°矫正至55°±11°(t = 4.931,P < 0.05),顶椎平移和胸椎后凸有轻微改善。胸廓平均高度从(13.3±2.0)cm增加到(17.2±2.4)cm(t = 8.365,P < 0.001),平均T1-S1高度从(24.4±3.8)cm增加到(32.5±5.3)cm(t = 9.080,P < 0.001)。在初次植入VEPTR器械后,每次撑开手术胸廓高度和T1-S1高度的平均增加量分别为(0.8±0.3)cm和(1.8±0.4)cm。6例患者出现8种并发症,包括肋骨支架移位、切口感染、术中胸膜破裂和腰椎椎弓根螺钉松动。
VEPTR技术被证明是预防早发性脊柱侧弯患者侧弯进展并允许脊柱和胸廓生长的有效方法。然而,由于并发症发生率相对较高,该技术的适应证需要严格选择。