Vernea J
Clin Exp Neurol. 1979;16:241-9.
The absolute and relative motor refractory periods and the range of motor conduction velocity were investigated in 25 normal subjects and in 25 patients suffering from peripheral neuropathy. The refractory periods were examined by a collision method, which eliminates the effect of the first of the paired stimuli, thus allowing the effect of the second stimulus to be clearly recorded. The range of conduction velocity was also examined by a collision method, and the conduction times were corrected by subtracting the absolute and relative refractory periods from the figures given by this method. The maximum motor conduction velocities obtained with this technique closely corresponded with those found using conventional methods. The results show that the refactory periods are prolonged and the conduction velocities are reduced in peripheral neuropathies, especially of segmental demyelination type, but the range of conduction velocity is not necessarily increased. The failure to suppress fully the effect of the proximal stimulus by a distal stimulus is a phenomenon found in peripheral neuropathies.
对25名正常受试者和25名患有周围神经病的患者进行了绝对和相对运动不应期以及运动传导速度范围的研究。通过碰撞法检查不应期，该方法消除了成对刺激中第一个刺激的影响，从而能够清晰记录第二个刺激的效果。传导速度范围也通过碰撞法进行检查，并且通过从该方法给出的数值中减去绝对和相对不应期来校正传导时间。用该技术获得的最大运动传导速度与使用传统方法测得的速度密切相符。结果表明，周围神经病，尤其是节段性脱髓鞘型周围神经病，其不应期延长，传导速度降低，但传导速度范围不一定增加。远端刺激不能完全抑制近端刺激的效应是周围神经病中发现的一种现象。
