正常和患病人类骨骼肌中的牛磺酸。

Taurine in normal and diseased human skeletal muscle.

作者信息

Airaksinen E M, Paljärvi L, Partanen J, Collan Y, Laakso R, Pentikäinen T

机构信息

Department of Paediatrics, University of Kuopio, Finland.

出版信息

Acta Neurol Scand. 1990 Jan;81(1):1-7. doi: 10.1111/j.1600-0404.1990.tb00923.x.

DOI:10.1111/j.1600-0404.1990.tb00923.x

PMID:2330810

Abstract

Taurine content of 199 clinical muscle biopsies was determined and correlated to histometric data of 121 cases. Taurine concentration in muscles was markedly dependent on fiber type distribution, taurine being more abundant in the slow, oxidative type 1 fibers than in the type 2 fibers. Taurine concentration rose slightly with age and tended to be higher in denervations, muscular dystrophies and myotonias, but the differences from the control values were non-significant.

摘要

测定了199份临床肌肉活检样本中的牛磺酸含量，并将其与121例病例的组织测量数据进行关联分析。肌肉中的牛磺酸浓度明显取决于纤维类型分布，牛磺酸在慢肌、氧化型1型纤维中比在2型纤维中更为丰富。牛磺酸浓度随年龄略有上升，在去神经支配、肌肉营养不良和肌强直中往往较高，但与对照值的差异无统计学意义。