一例核型为45,X,-X,i dic(7q)的肾淋巴管瘤。

A case of renal lymphangioma with a karyotype 45,X,-X,i dic(7q).

作者信息

Debiec-Rychter M, Kałuzewski B, Saryusz-Wolska H, Jankowska J

机构信息

Department of Medical Genetics, Medical Academy of Lodz, Poland.

出版信息

Cancer Genet Cytogenet. 1990 May;46(1):29-33. doi: 10.1016/0165-4608(90)90005-u.

DOI:10.1016/0165-4608(90)90005-u

PMID:2331680

Abstract

Cytogenetic analysis of a polycystic unilateral renal lymphangioma was performed by short-term culture and banding methods. The tumor's cells showed an isochromosome of the long arm of chromosome #7 and monosomy of X chromosome, whereas the peripheral lymphocytes stimulated with phytohemagglutinin showed a normal female karyotype, 46,XX. These karyotypic anomalies suggest that lymphangioma, although clinically benign, may have malignant potential.

摘要

采用短期培养和显带方法对一例多囊性单侧肾淋巴管瘤进行了细胞遗传学分析。肿瘤细胞显示7号染色体长臂等臂染色体和X染色体单体，而经植物血凝素刺激的外周淋巴细胞显示正常女性核型，46,XX。这些核型异常提示，淋巴管瘤尽管临床为良性，但可能具有恶性潜能。