Gerber L M, Schnall P L, Pickering T G
Department of Medicine, New York Hospital-Cornell University Medical College, NY 10021.
Hypertension. 1990 May;15(5):508-13. doi: 10.1161/01.hyp.15.5.508.
This study was undertaken to evaluate the associations of body fat and its distribution with casual and ambulatory blood pressure in nonobese men. One hundred and thirty-five normotensive or mildly hypertensive (but untreated) men employed at three work sites were studied. Casual blood pressure was measured at the work site at initial screening and on a second occasion by a nurse. Ambulatory blood pressure was measured noninvasively for 24 hours on a workday and analyzed as work, home, and sleep blood pressure measurements. Anthropometric measurements included height, weight, and waist and hip circumferences. Blood pressure was highest while at work; home blood pressure was higher than screening blood pressure or nurse blood pressure, and sleep blood pressure was lowest. Weight and both waist and hip circumferences (but not their ratio) were all significantly correlated with screening, nurse, and sleep blood pressures but not with work or home blood pressures. Stepwise regression analysis showed that waist circumference was the best overall predictor of blood pressure. We suggest that in situations where blood pressure is the dependent variable, correlations with other variables may be closest for "basal" measures of blood pressure and may be obscured by the effects of daily activities on blood pressure.
本研究旨在评估非肥胖男性体脂及其分布与偶测血压和动态血压之间的关联。对在三个工作场所工作的135名血压正常或轻度高血压(但未经治疗)的男性进行了研究。在初次筛查时以及第二次由护士在工作场所测量偶测血压。在工作日对动态血压进行24小时无创测量,并分析工作、家庭和睡眠时的血压测量值。人体测量指标包括身高、体重、腰围和臀围。工作时血压最高;家庭血压高于筛查血压或护士测量的血压,睡眠时血压最低。体重以及腰围和臀围(但不包括它们的比值)均与筛查血压、护士测量的血压和睡眠血压显著相关,但与工作血压或家庭血压无关。逐步回归分析表明,腰围是血压的最佳总体预测指标。我们建议,在以血压为因变量的情况下,与其他变量的相关性可能在血压的“基础”测量中最为密切,并且可能会被日常活动对血压的影响所掩盖。