松狮犬疑似家族性肾病。
Suspected familial renal disease in chow chows.
作者信息
Brown C A, Crowell W A, Brown S A, Barsanti J A, Finco D R
机构信息
Department of Veterinary Pathology, College of Veterinary Medicine, University of Georgia, Athens 30602.
出版信息
J Am Vet Med Assoc. 1990 Apr 15;196(8):1279-84.
Renal disease was diagnosed in 6 young Chow Chows. Clinical abnormalities included vomiting, polyuria, polydipsia, and weight loss. Common abnormal laboratory findings were azotemia, hyperphosphatemia, hypocalcemia, nonregenerative anemia, and low urine specific gravity. All 6 dogs had similar microscopic renal lesions. characterized by interstitial fibrosis, a population of small glomeruli, and lack of inflammatory cells. A familial basis for the renal disease is suggested because of its development in 4 closely related dogs.
6只年轻的 Chow Chow犬被诊断出患有肾脏疾病。临床异常表现包括呕吐、多尿、多饮和体重减轻。常见的实验室异常结果为氮质血症、高磷血症、低钙血症、非再生性贫血和低尿比重。所有6只犬都有相似的肾脏微观病变，其特征为间质纤维化、一小群肾小球以及缺乏炎性细胞。由于该疾病在4只亲缘关系密切的犬中出现，提示其有家族性基础。
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