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使用绿光™磷酸钛氧钾激光经尿道凝固治疗放射性出血性膀胱炎

Transurethral coagulation for radiation-induced hemorrhagic cystitis using Greenlight™ potassium-titanyl-phosphate laser.

作者信息

Zhu Jin, Xue Boxin, Shan Yuxi, Yang Dongrong, Zang Yachen

机构信息

Department of Urology, the Second Affiliated Hospital of Soochow University, Suzhou City, Jiangsu Province, China.

出版信息

Photomed Laser Surg. 2013 Feb;31(2):78-81. doi: 10.1089/pho.2012.3396. Epub 2013 Jan 17.

Abstract

OBJECTIVE

The aim of this study was to to demonstrate the initial treatment outcomes of Greenlight™ potassium-titanyl-phosphate (KTP) laser on radiation-induced hemorrhagic cystitis.

BACKGROUND DATA

Hemorrhagic cystitis is a common complication of radiation therapy for pelvic tumors.

MATERIALS AND METHODS

From September 2004 to February 2011, 10 patients with radiation-induced intractable hemorrhagic cystitis underwent transurethral Greenlight KTP laser coagulation of the bladder. The power setting was limited to 20-30 W.

RESULTS

Bleeding stopped in all cases after one session of laser treatment. Mean follow-up time was 17 months (6-36 months). All patients underwent cystoscopy 3 months postoperatively, and no bleeding or significant scar was found. Recurrence of significant bleeding was seen in one case 7 months post-operation, and was again cured by KTP laser. There were no complications from the procedures.

CONCLUSIONS

Our experience suggests that transurethral coagulation using KTP laser is a safe and effective strategy for the treatment of hemorrhagic radiation cystitis.

摘要

目的

本研究旨在证明格林莱特™磷酸钛氧钾(KTP)激光治疗放射性出血性膀胱炎的初步治疗效果。

背景资料

出血性膀胱炎是盆腔肿瘤放射治疗的常见并发症。

材料与方法

2004年9月至2011年2月,10例放射性难治性出血性膀胱炎患者接受了经尿道格林莱特KTP激光膀胱凝固术。功率设置限制在20 - 30瓦。

结果

所有病例经一次激光治疗后出血停止。平均随访时间为17个月(6 - 36个月)。所有患者术后3个月接受膀胱镜检查,未发现出血或明显瘢痕。1例患者术后7个月出现严重出血复发,再次经KTP激光治愈。手术无并发症发生。

结论

我们的经验表明,经尿道使用KTP激光凝固术是治疗放射性出血性膀胱炎的一种安全有效的策略。

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