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澳大利亚国家心脏基金会心房颤动导管消融治疗共识声明。

National Heart Foundation of Australia consensus statement on catheter ablation as a therapy for atrial fibrillation.

机构信息

Department of Cardiology, Royal Melbourne Hospital, Melbourne, VIC, Australia.

出版信息

Med J Aust. 2013 Jan 21;198(1):27-8. doi: 10.5694/mja12.10929.

DOI:10.5694/mja12.10929
PMID:23330766
Abstract

Atrial fibrillation (AF) is estimated to affect 1%-2% of the population. It is increasing in prevalence and is associated with excess mortality, considerable morbidity and hospitalisations. AF is responsible for a significant and growing societal financial burden. Catheter ablation is an increasingly used therapeutic strategy for the management of AF; however, some confusion exists among those caring for patients with this condition about the role and optimal use of ablative treatments for AF. Our aim in this consensus statement is to provide recommendations on the use of primary catheter ablation for AF in Australia, on the basis of current evidence. Our consensus is that the primary indication for catheter ablation of AF is the presence of symptomatic AF that is refractory or intolerant to at least one Class 1 or Class 3 antiarrhythmic medication. In selecting patients for catheter ablation of AF, consideration should be given to the patient's age, duration of AF, left atrial size and the presence of significant structural heart disease. Best results are obtained in younger patients with paroxysmal AF, no structural heart disease and smaller atria. Ablation techniques for patients with persistent AF are still undergoing evaluation. Discontinuation of warfarin or equivalent therapies is not considered a sole indication for this procedure. After AF ablation, anticoagulation therapy is generally recommended for all patients for at least 1-3 months. Discontinuation of warfarin or equivalent therapies after ablation is generally not recommended in patients who have a CHADS 2 score (congestive heart failure, hypertension, age ≥ 75 years, diabetes, 1 point each; prior stroke or transient ischaemic attack, 2 points) of ≥ 2.

摘要

心房颤动(AF)估计影响 1%-2%的人口。它的发病率正在增加,与死亡率过高、发病率高和住院率高有关。AF 给社会带来了巨大的经济负担。导管消融术是一种越来越被用于治疗 AF 的治疗策略;然而,对于那些治疗这种疾病的患者,关于消融治疗 AF 的作用和最佳使用存在一些混淆。我们在本共识声明中的目的是根据当前证据,就澳大利亚 AF 的初始导管消融治疗提出使用建议。我们的共识是,AF 导管消融的主要适应证是存在对至少一种 1 类或 3 类抗心律失常药物不耐受或难治的症状性 AF。在选择接受 AF 导管消融的患者时,应考虑患者的年龄、AF 的持续时间、左心房大小以及是否存在严重结构性心脏病。在没有结构性心脏病且心房较小的阵发性 AF 年轻患者中,获得的效果最佳。持续性 AF 患者的消融技术仍在评估中。停止华法林或等效治疗不被认为是该程序的唯一适应证。AF 消融后,一般建议所有患者至少抗凝治疗 1-3 个月。对于 CHADS 2 评分(充血性心力衰竭、高血压、年龄≥75 岁、糖尿病,各 1 分;既往卒中或短暂性脑缺血发作,2 分)≥2 的患者,消融后一般不建议停止华法林或等效治疗。

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1
National Heart Foundation of Australia consensus statement on catheter ablation as a therapy for atrial fibrillation.澳大利亚国家心脏基金会心房颤动导管消融治疗共识声明。
Med J Aust. 2013 Jan 21;198(1):27-8. doi: 10.5694/mja12.10929.
2
Periprocedural stroke and bleeding complications in patients undergoing catheter ablation of atrial fibrillation with different anticoagulation management: results from the Role of Coumadin in Preventing Thromboembolism in Atrial Fibrillation (AF) Patients Undergoing Catheter Ablation (COMPARE) randomized trial.不同抗凝管理的房颤导管消融患者围术期卒中与出血并发症:来自华法林在房颤(AF)患者导管消融中预防血栓栓塞(COMPARE)随机试验的作用(Role of Coumadin in Preventing Thromboembolism in Atrial Fibrillation (AF) Patients Undergoing Catheter Ablation,COMPARE)的研究结果。
Circulation. 2014 Jun 24;129(25):2638-44. doi: 10.1161/CIRCULATIONAHA.113.006426. Epub 2014 Apr 17.
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Kardiol Pol. 2013;71(1):17-24.
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Very low risk of thromboembolic events in patients undergoing successful catheter ablation of atrial fibrillation with a CHADS2 score ≤3: a long-term outcome study.在 CHADS2 评分≤3 的房颤患者中,成功接受导管消融治疗后发生血栓栓塞事件的风险非常低:一项长期预后研究。
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Canadian Cardiovascular Society atrial fibrillation guidelines 2010: catheter ablation for atrial fibrillation/atrial flutter.加拿大心血管学会 2010 年心房颤动指南:心房颤动/心房扑动的导管消融治疗。
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Curr Cardiol Rep. 2016 Jul;18(8):71. doi: 10.1007/s11886-016-0747-4.
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Atrial fibrillation in the aging heart: pharmacological therapy and catheter ablation in the elderly.老年心脏中的心房颤动:老年人的药物治疗与导管消融
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Am J Cardiol. 2012 Aug 15;110(4):545-51. doi: 10.1016/j.amjcard.2012.04.028. Epub 2012 May 15.

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The importance of anaesthesia in atrial fibrillation ablation: Comparing conscious sedation with general anaesthesia.麻醉在心房颤动消融术中的重要性:清醒镇静与全身麻醉的比较。
Indian Pacing Electrophysiol J. 2023 Mar-Apr;23(2):47-52. doi: 10.1016/j.ipej.2022.12.001. Epub 2022 Dec 10.
2
Are left ventricular ejection fraction and left atrial diameter related to atrial fibrillation recurrence after catheter ablation?: A meta-analysis.左心室射血分数和左心房直径与导管消融术后房颤复发有关吗?一项荟萃分析。
Medicine (Baltimore). 2018 May;97(20):e10822. doi: 10.1097/MD.0000000000010822.