使用诺瓦利斯（Novalis）进行分次立体定向放射治疗小儿局限性眶内视神经胶质瘤。
Fractionated stereotactic radiotherapy using Novalis for confined intra-orbital optic nerve glioma in pediatric patient.
作者信息
Han Seong Rok, Kim Keung Nyun, Yee Gi-Taek, Choi Chan Young, Lee Dong Joon, Sohn Moon Jun, Lee Chae Heuck
机构信息
Graduate School, College of Medicine, Yonsei University, Seoul, South Korea.
出版信息
Childs Nerv Syst. 2013 May;29(5):867-71. doi: 10.1007/s00381-013-2031-x. Epub 2013 Jan 22.
INTRODUCTION
Optic gliomas are the most common tumors in the optic pathways during childhood. Among them, about 10 % are located within intra-orbital cavity. However, the optimal management for intra-orbital optic nerve gliomas remains controversial. An 11-year-old male complained about progressive decline of vision in his right eye. Brain MRI revealed a fusiform enlargement of right optic nerve within intra-orbital cavity.
MATERIALS AND METHODS
A presumptive diagnosis of optic nerve glioma was made. Therefore, we performed fractionated stereotactic radiotherapy (FSRT) using Novalis.
DISCUSSION
Five years after FSRT treatment, follow-up MRI revealed size reduction of tumor and visual acuity improvement without radiation-related complications.
引言
视神经胶质瘤是儿童期视神经通路中最常见的肿瘤。其中，约10%位于眶内。然而，眶内视神经胶质瘤的最佳治疗方法仍存在争议。一名11岁男性主诉右眼视力逐渐下降。脑部磁共振成像（MRI）显示眶内右侧视神经呈梭形增粗。
材料与方法
做出了视神经胶质瘤的初步诊断。因此，我们使用诺力刀（Novalis）进行了分次立体定向放射治疗（FSRT）。
讨论
FSRT治疗五年后，随访MRI显示肿瘤缩小，视力改善，且无放疗相关并发症。
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