Evsen Mehmet Siddik, Sak Muhammet Erdal, Soydine Hatice Ender, Basaranoglu Serdar, Bakir Cetin, Sak Sibel, Gul Talip
Dicle University, School of Medicine, Department of Obstetrics and Gynecology, Diyarbakir, Turkey.
Ginekol Pol. 2012 Sep;83(9):665-8.
To evaluate the outcomes of bilateral internal iliac artery ligation (IIAL) in severe postpartum hemorrhage (PPH).
Multi-center retrospective study.
The study was performed from January 2005 to December 2010, at the Obstetrics and Gynecology Clinic, Dicle University Medical Faculty and Maternity Hospital, Diyarbakir, Turkey. Life-threatening cases of severe postpartum hemorrhage, which could not be controlled with conservative medical and surgical treatments and finally managed with IIAL, were retrospectively evaluated.
Totally 53 patients who underwent IIAL procedures were included in the study. All patients were hemodynamically unstable. The mean shock index and transfused units of blood were 1.17 +/- 0.46, 5.49 +/- 3.04, respectively. Uterine atony was the leading cause of severe postpartum hemorrhage and the need for IIAL. Coagulopathy developed in 26 (49.1%) patients during the postoperative follow-up period. Uterus was preserved in 17 (32.0%) cases. Three patients died of complications and/or morbidity associated with hemorrhage.
Serious PPH is most frequently associated with uterine atony and IIAL should be considered in cases with severe PPH unresponsive to other treatment modalities. If, in the antenatal period, patients have risk factors of postpartum hemorrhage, they must be transferred to appropriate centers to prevent a possibly fatal outcome.
评估双侧髂内动脉结扎术(IIAL)治疗严重产后出血(PPH)的效果。
多中心回顾性研究。
本研究于2005年1月至2010年12月在土耳其迪亚巴克尔市的狄克莱大学医学院妇产科诊所和妇产医院进行。对危及生命的严重产后出血病例进行回顾性评估,这些病例经保守药物和手术治疗无法控制,最终采用IIAL治疗。
共有53例行IIAL手术的患者纳入本研究。所有患者血流动力学均不稳定。平均休克指数和输血量分别为1.17±0.46、5.49±3.04。宫缩乏力是严重产后出血及需要行IIAL的主要原因。26例(49.1%)患者在术后随访期间出现凝血功能障碍。17例(32.0%)患者子宫得以保留。3例患者死于与出血相关的并发症和/或疾病。
严重PPH最常与宫缩乏力相关,对于其他治疗方式无效的严重PPH病例应考虑行IIAL。如果在产前患者有产后出血的危险因素,必须将其转至合适的中心以防止可能的致命后果。