Laboratory of Electrophysiology, The Secondary Medical College, Guangzhou University of Traditional Chinese Medicine, Guangzhou 510120, China ; Key Laboratory of Acupuncture of Guangdong Province, Guangzhou University of Traditional Chinese Medicine, Guangzhou 510006, China.
Evid Based Complement Alternat Med. 2012;2012:753264. doi: 10.1155/2012/753264. Epub 2012 Dec 31.
Acupuncture has a reflex regulation in gastrointestinal functions, which is characterized with segment. In the present study, the neural pathway of electroacupuncture (EA) at orofacial acupoints (ST2) on gastric myoelectric activity (GMA) in rats was investigated. The results indicated that EA at ST2 facilitated spike bursts of GMA, which is similar to EA at limbs and opposite to EA at abdomen. The excitatory effect was abolished by the transaction of infraorbital nerves, dorsal vagal complex lesion, and vagotomy, respectively. In addition, microinjection of L-glutamate into the nucleus of the solitary tract (NTS) attenuated the excitatory effect. All these data suggest that the dorsal vagal complex is involved in the reflex regulation of EA at orofacial acupoints on gastric functions and NTS-dorsal motor nucleus of the vagus (DMV) inhibitory connections may be essential for it.
针刺对胃肠道功能具有反射调节作用,其特点具有节段性。本研究探讨了电针对大鼠口腔穴位(ST2)胃肌电活动(GMA)的神经通路。结果表明,ST2 的电刺激促进了 GMA 的爆发性放电,其作用与四肢的电刺激相似,与腹部的电刺激相反。眶下神经切断术、迷走神经背核损伤和迷走神经切断术分别消除了兴奋作用。此外,将 L-谷氨酸微注射到孤束核(NTS)中可减弱兴奋作用。所有这些数据表明,迷走神经背核参与了口腔穴位针刺对胃功能的反射调节,而 NTS-迷走神经背运动核(DMV)抑制性连接可能是其必需的。