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开发一种新的、快速的、用户友好的射线追踪程序“CSIM”,用于模拟平行孔准直器。

Development of a new, fast, user friendly, ray tracing program "CSIM" for the simulation of parallelhole collimators.

机构信息

Physics Department, University of Pisa and INFN, Pisa, Italy.

出版信息

Comput Methods Programs Biomed. 2013 Jun;110(3):290-7. doi: 10.1016/j.cmpb.2012.12.004. Epub 2013 Jan 21.

DOI:10.1016/j.cmpb.2012.12.004
PMID:23347780
Abstract

We have developed a fast, user friendly, ray-tracing program, "CSIM" for low-energy gamma rays (up to ∼200keV) to simulate the performance characteristics of parallelhole collimators. We have used a ray-tracing approach to find the sensitivity and resolution of the parallelhole collimator by including the penetration of photons through the collimator due to the finite attenuation of the collimator material. "CSIM" can calculate the sensitivity of the collimator, the geometric and penetrating photon ratios, and the 1D and 2D point source response functions (PSF) with the statistical uncertainty for different hole shapes (e.g. square, hexagonal, and cylindrical). We have used "CSIM" to simulate the collimator of the YAP-(S)PETII small animal scanner. We present the analysis of the YAP-(S)PETII scanner round-hole parallel collimator designed for nuclear medicine imaging at 140keV. For this aim, different designs have been considered for a variety of source-collimator distances (b=5, 10, 15, 20cm). Resolution and sensitivity characteristics have been plotted as a function of the collimator thickness and the diameter of the hole. For each value of the source-collimator distance, and for each collimator thickness investigated, the trade-off between sensitivity and spatial resolution has been given as a series of characteristic curves. Then, we compare our simulated resolution and sensitivity results to the analytically calculated ones and found that the analytically calculated results for the YAP-(S)PETII scanner collimator are not far away the results predicted by CSIM and also with the experimentally measured resolution values.

摘要

我们开发了一个快速、用户友好的射线追踪程序“CSIM”,用于模拟低能伽马射线(最高约 200keV)的性能特征。我们使用射线追踪方法,通过包括光子通过由于有限的衰减而穿透准直器的穿透,来找到平行孔准直器的灵敏度和分辨率。“CSIM”可以计算准直器的灵敏度、几何和穿透光子比以及 1D 和 2D 点源响应函数(PSF),并具有不同孔形状(例如方形、六边形和圆柱形)的统计不确定性。我们使用“CSIM”模拟了 YAP-(S)PETII 小动物扫描仪的准直器。我们分析了为核医学成像设计的 140keV YAP-(S)PETII 扫描仪的圆形平行孔平行准直器。为此,考虑了不同的设计,适用于各种源-准直器距离(b=5、10、15、20cm)。将分辨率和灵敏度特性作为准直器厚度和孔直径的函数进行绘制。对于每个源-准直器距离的值,并且对于研究的每个准直器厚度,给出了灵敏度和空间分辨率之间的权衡作为一系列特征曲线。然后,我们将我们的模拟分辨率和灵敏度结果与分析计算的结果进行比较,发现 YAP-(S)PETII 扫描仪准直器的分析计算结果与 CSIM 预测的结果相差不远,并且与实验测量的分辨率值也相符。

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