[The clinical significance of immunoglobulin E in chronic liver diseases].

The rise of the IgE content was found in 78.5% of patients suffering from chronic liver diseases. In patients with chronic active hepatitis, it was identified to a greater rate, whereas in patients with chronic persistent hepatitis to a lesser degree. A direct relation was noted between the level of IgE and the intensity of the disease clinical picture, biochemical and immunological indicators of activity, and the degree of morphological alterations in the liver. It is concluded that the immediate hypersensitivity is implicated in the pathogenesis of chronic liver diseases.