Gallardo Hernández Ana, Revilla Monsalve Cristina, Fridman Leonid, Leder Ron, Islas Andrade Sergio, Shtessel Yuri
Unidad de Investigación en Enfermedades Metabólicas, Centro Médico Nacional Siglo XXI (IMSS), México.
Annu Int Conf IEEE Eng Med Biol Soc. 2012;2012:2056-9. doi: 10.1109/EMBC.2012.6346363.
Theoretically High-Order Sliding-Mode Controllers are well suited to perform closed loop glucose regulation because they are insensitive to parameter uncertainties and robust to unknown dynamics that may perturb the system. The implementation of the controller based on the concept of practical relative degree is presented. The controller was tested in Sprague-Dawley rats with steptozotocin induced diabetes. The tests demonstrated high efficacy and robustness of the controller.
理论上,高阶滑模控制器非常适合进行闭环血糖调节,因为它们对参数不确定性不敏感,并且对可能干扰系统的未知动态具有鲁棒性。本文提出了基于实际相对度概念的控制器实现方法。该控制器在链脲佐菌素诱导糖尿病的Sprague-Dawley大鼠中进行了测试。测试证明了该控制器具有高效性和鲁棒性。