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原发性先天性青光眼的小梁切开术联合改良小梁切除术

Combined trabeculotomy and augmented trabeculectomy in primary congenital glaucoma.

作者信息

Shakir Munira, Bokhari Aisha, Kamil Zeeshan, Zafar Shakir

机构信息

Department of Ophthalmology, L.R.B.T Free Base Eye Hospital, Karachi.

出版信息

J Coll Physicians Surg Pak. 2013 Feb;23(2):116-9.

Abstract

OBJECTIVE

To evaluate the results of combined trabeculotomy and augmented trabeculectomy as a primary procedure on intraocular pressure and corneal clarity in uncomplicated congenital glaucoma.

STUDY DESIGN

A case series.

PLACE AND DURATION OF STUDY

L.R.B.T Free Base Eye Hospital, Karachi, from January 2007 to December 2010.

METHODOLOGY

Twenty eyes of 14 consecutive children with primary congenital glaucoma who had primary trabeculotomy and augmented trabeculectomy were observed from January 2007 to December 2010 at LRBT Free Base Eye Hospital, Karachi. Main outcome measures were pre-operative and postoperative intraocular pressure, corneal clarity and complications.

RESULTS

Out of 14 patients, 9 patients (64.2%) were male and 5 patients (35.7%) were female with age ranging between 5 months to 6 years. Mean duration of follow-up was 8.25 months. Seventeen eyes (85%) showed improvement in corneal clarity from baseline at their last follow-up. Mean intraocular pressure decreased from 32 ± 2.5 mmHg pre-operatively to 13 ± 2.5 mmHg postoperatively at the last follow-up (p < 0.001). Complete success (intraocular pressure < 20 mmHg) was obtained in 16 (80%) out of 20 eyes. Complications encountered were vitreous loss per-operatively while performing iridectomy in 1 eye (5%), shallow anterior chamber on the first postoperative day in 1 eye (5%) and hyphema in 1 eye (5%).

CONCLUSION

Combined trabeculotomy and augmented trabeculectomy for primary congenital glaucoma resulted in improvement in reduction of intraocular pressure as well as improvement in corneal clarity. Hence, combined trabeculotomy and augmented trabeculectomy is a safe and effective procedure for primary congenital glaucoma.

摘要

目的

评估小梁切开术联合改良小梁切除术作为原发性先天性青光眼的初始手术对眼压和角膜透明度的影响。

研究设计

病例系列研究。

研究地点和时间

2007年1月至2010年12月,卡拉奇的LRBT免费基础眼科医院。

方法

2007年1月至2010年12月,在卡拉奇的LRBT免费基础眼科医院对14例连续患有原发性先天性青光眼并接受原发性小梁切开术联合改良小梁切除术的儿童的20只眼睛进行了观察。主要观察指标为术前和术后眼压、角膜透明度及并发症。

结果

14例患者中,男性9例(64.2%),女性5例(35.7%),年龄在5个月至6岁之间。平均随访时间为8.25个月。17只眼睛(85%)在最后一次随访时角膜透明度较基线有所改善。最后一次随访时,平均眼压从术前的32±2.5 mmHg降至术后的13±2.5 mmHg(p<0.001)。20只眼睛中有16只(80%)获得完全成功(眼压<20 mmHg)。术中并发症包括1只眼睛(5%)在进行虹膜切除术时发生玻璃体脱出,1只眼睛(5%)在术后第一天出现浅前房,1只眼睛(5%)出现前房积血。

结论

小梁切开术联合改良小梁切除术治疗原发性先天性青光眼可降低眼压并改善角膜透明度。因此,小梁切开术联合改良小梁切除术是治疗原发性先天性青光眼的一种安全有效的手术方法。

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