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射频消融术治疗小儿微囊型淋巴管畸形

Radiofrequency ablation in the treatment of paediatric microcystic lymphatic malformations.

作者信息

Goswamy J, Penney S E, Bruce I A, Rothera M P

机构信息

Department of Paediatric Otolaryngology, Royal Manchester Children's Hospital, Manchester, UK.

出版信息

J Laryngol Otol. 2013 Mar;127(3):279-84. doi: 10.1017/S0022215113000029. Epub 2013 Feb 4.

Abstract

OBJECTIVE

Congenital lymphatic malformations are a challenging clinical problem. There is currently no universally accepted treatment for the management of microcystic disease. We describe the novel use of an existing technology (radiofrequency ablation, also termed Coblation) for the debulking of paediatric microcystic lymphatic malformations involving the upper aerodigestive tract.

METHODS

Five children with microcystic or mixed-type lymphatic malformations were included in this retrospective case series.

RESULTS

Each child had a satisfactory outcome following radiofrequency debulking, with improved oral intake and airway symptoms. No serious complications were reported. These findings constitute level IV evidence.

CONCLUSION

We recommend radiofrequency ablation as a safe, viable alternative to existing techniques for the treatment of paediatric microcystic lymphatic malformations of the upper aerodigestive tract. Radiofrequency ablation achieves effective debulking of microcysts whilst avoiding excessive bleeding and thermal damage to surrounding tissues. This paper constitutes the first report of successful treatment of airway obstruction due to paediatric laryngopharyngeal microcystic disease, using radiofrequency ablation.

摘要

目的

先天性淋巴管畸形是一个具有挑战性的临床问题。目前对于微囊型疾病的治疗尚无普遍接受的方法。我们描述了一种现有技术(射频消融,也称为低温等离子消融)在治疗累及上呼吸道消化道的小儿微囊型淋巴管畸形减容方面的新用途。

方法

本回顾性病例系列纳入了5例患有微囊型或混合型淋巴管畸形的儿童。

结果

射频减容术后每个患儿均取得了满意的效果,经口摄入量和气道症状均有改善。未报告严重并发症。这些发现构成IV级证据。

结论

我们推荐射频消融作为治疗小儿上呼吸道消化道微囊型淋巴管畸形的现有技术的一种安全、可行的替代方法。射频消融可有效减少微囊肿的体积,同时避免过度出血和对周围组织的热损伤。本文是关于使用射频消融成功治疗小儿喉咽微囊型疾病所致气道梗阻的首次报告。

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