肥胖与肾移植。

Obesity and kidney transplantation.

机构信息

Division of Nephrology, Medical University of South Carolina, Charleston, SC 29425, USA.

出版信息

Semin Nephrol. 2013 Jan;33(1):34-43. doi: 10.1016/j.semnephrol.2012.12.007.

DOI:10.1016/j.semnephrol.2012.12.007

Abstract

Obesity confers increased risk for graft loss and death among renal transplant recipients. However the relationship of changes in body weight and composition to outcome on the transplant waitlist and post-transplantation is not straightforward. Strategies to manage weight in the waitlisted patient and after kidney transplantation must be performed in the context of a multidisciplinary approach and individualized based on risk factors in particular patients. Although retrospective studies offer considerable insights into the relationship between obesity and kidney transplant outcome, causal inferences must be made with great caution.

摘要

肥胖会增加肾移植受者移植物丢失和死亡的风险。然而，体重和成分的变化与移植等待名单和移植后的结果之间的关系并不简单。在多学科方法的背景下，并根据特定患者的风险因素，必须在等待移植的患者和肾移植后进行管理体重的策略。虽然回顾性研究为肥胖与肾移植结果之间的关系提供了相当多的见解，但必须非常谨慎地进行因果推断。