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Central pontine myelinolysis presenting with tremor in a child with celiac disease.

作者信息

Sharma Preeti, Sharma Suvasini, Panwar Neha, Mahto Deonath, Kumar Praveen, Kumar Atin, Aneja Satinder

机构信息

1Department of Pediatrics, Lady Hardinge Medical College and associated Kalawati Saran Children's Hospital, New Delhi, India.

出版信息

J Child Neurol. 2014 Mar;29(3):381-4. doi: 10.1177/0883073812475086. Epub 2013 Feb 5.

Abstract

A 4-year-old boy presented with a history of tremor for 7 days. He also had recurrent diarrhea for the previous 1 year, and poor weight gain. Magnetic resonance of the brain was suggestive of central pontine myelinolysis. There was no evidence of electrolyte abnormalities. The serum tissue transglutaminase level was markedly elevated, and the duodenal biopsy revealed features of celiac disease. The patient was started on gluten-free diet. The tremor resolved within 3 months. Repeat imaging of the brain done 3 months after starting gluten-free diet showed complete resolution of the lesion. This case highlights the unusual presentation of central pontine myelinosis as tremor in a malnourished child with celiac disease.

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