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经肛门内镜微创手术的并发症罕见且轻微:单机构的分析及与现有数据的比较。

Complications of transanal endoscopic microsurgery are rare and minor: a single institution's analysis and comparison to existing data.

机构信息

MedStar Washington Hospital Center, Section of Colon and Rectal Surgery, Washington, DC 20020-2975, USA.

出版信息

Dis Colon Rectum. 2013 Mar;56(3):295-300. doi: 10.1097/DCR.0b013e31827163f7.

Abstract

BACKGROUND

Transanal endoscopic microsurgery, a minimally invasive procedure for treatment of early-stage rectal cancer, carcinoid tumors, and adenomas, is shown to be a safe procedure with very low perioperative morbidity.

OBJECTIVE

We aimed to compare the outcomes of transanal endoscopic microsurgery at a large volume tertiary care center with the existing literature.

DESIGN

We retrospectively reviewed a prospectively collected database of 325 transanal endoscopic microsurgery procedures and looked for risk factors associated with complications. Indications for transanal endoscopic microsurgery included rectal adenocarcinomas, adenomas, and carcinoids.

SETTING

Procedures were performed by a single surgeon at a large-volume tertiary care center.

PATIENTS

Patients were enrolled over a 20-year period, and data were collected on demographics, perioperative details, tumor characteristics, and complications.

INTERVENTIONS

Transanal endoscopic microsurgery was performed on all 325 patients.

MAIN OUTCOME MEASURES

Main outcome measures were urinary retention, late bleeding requiring intervention, dehiscence, peritoneal cavity entry, conversion to abdominal approach, fecal soiling, and rectovaginal fistula.

RESULTS

Intraoperative bleeding was associated with larger tumor size, whereas postoperative bleeding requiring intervention was not associated with any factors studied. Peritoneal cavity entry and urinary retention were more likely if the tumor was in either the anterior or lateral position in the rectum. The peritoneal cavity was entered in 9 patients, and conversion to abdominal approach occurred in 1 patient. Intraoperative bleeding, by surgeon's choice, and urinary retention, by patient's choice, were associated with a greater likelihood of admission to the inpatient ward. Fecal soiling was not reported by patients and not recorded.

LIMITATIONS

This study was limited because it was a retrospective analysis

CONCLUSIONS

Transanal endoscopic microsurgery is an extremely safe procedure, offering very low perioperative morbidity. The overall morbidity found in our study was 10.5%, on par with published data for large series of 21%, 7.7%, and 14.9%. In contrast, complications from radical resection are reported at 18% to 55%.

摘要

背景

经肛门内镜微创手术是一种治疗早期直肠癌、类癌肿瘤和腺瘤的微创方法,已被证明是一种安全的手术,围手术期发病率非常低。

目的

我们旨在将大型三级保健中心的经肛门内镜微创手术结果与现有文献进行比较。

设计

我们回顾性地分析了一项前瞻性收集的 325 例经肛门内镜微创手术的数据库,并寻找与并发症相关的危险因素。经肛门内镜微创手术的适应证包括直肠腺癌、腺瘤和类癌。

设置

该手术由一位经验丰富的外科医生在一家大型三级保健中心进行。

患者

在 20 年的时间里,患者被纳入研究,并收集了人口统计学、围手术期细节、肿瘤特征和并发症的数据。

干预措施

所有 325 例患者均行经肛门内镜微创手术。

主要观察指标

主要观察指标为尿潴留、需要干预的迟发性出血、裂开、腹腔进入、转为剖腹手术、粪便污染和直肠阴道瘘。

结果

术中出血与肿瘤较大有关,而术后需要干预的出血与研究的任何因素均无关。如果肿瘤位于直肠的前位或侧位,则更有可能发生腹腔进入和尿潴留。9 例患者发生腹腔进入,1 例患者转为剖腹手术。术中出血(由外科医生选择)和尿潴留(由患者选择)与更有可能住院有关。粪便污染未被患者报告,也未记录。

局限性

本研究为回顾性分析,存在一定局限性。

结论

经肛门内镜微创手术是一种非常安全的手术,围手术期发病率极低。我们的研究中发现的总发病率为 10.5%,与发表的 21%、7.7%和 14.9%的大型系列研究结果相当。相比之下,根治性切除的并发症发生率为 18%至 55%。

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