Department of Paediatric Orthopaedics, Royal National Orthopaedic Hospital, London, UK.
BMJ Open. 2013 Feb 8;3(2). doi: 10.1136/bmjopen-2012-002276. Print 2013.
OBJECTIVES: In the UK there are approximately 850 000 new fractures seen each year. Rates of non-union of 5-10% of fractures have been suggested, the cost to the National Health Service of treating non-union has been reported to range between £7000 and £79 000 per person yet there are little actual data available. The objective of this epidemiological study therefore is for the first time to report the rates of fracture non-union. DESIGN: A cross-sectional epidemiological study. SETTING: The population of Scotland. PARTICIPANTS: All patient admissions to hospital in Scotland are coded according to diagnosis. These data are collected by (and were obtained from) Information Services Department Scotland. Those who have been coded for a bone non-union between 2005 and 2010 were included in the study. No patients were excluded. Population data were obtained from the Registrar General for Scotland. OUTCOME MEASURE: The number of fracture non-unions per 100 000 population of Scotland according to age, sex and anatomical distribution of non-union. RESULTS: 4895 non-unions were treated as inpatients in Scotland between 2005 and 2010, averaging 979 per year, with an overall incidence of 18.94 per 100 000 population per annum. The distribution according to gender was 57% male and 43% female. The overall peak incidence according to age was between 30 and 40 years. The mean population of Scotland between 2005 and 2010 was 5 169 140 people. CONCLUSION: Fracture non-union in the population as a whole remains low at less than 20 per 100 000 population and peaks in the fourth decade of life. Further research is required to determine the risk of non-union per fracture according to age/sex/anatomical distribution. .
目的:在英国,每年大约有 85 万例新骨折。有研究表明,骨折不愈合的发生率为 5-10%,据报道,英国国民保健服务系统治疗骨折不愈合的费用每人在 7000 英镑至 79000 英镑之间,但实际数据很少。因此,这项流行病学研究的目的是首次报告骨折不愈合的发生率。
设计:横断面流行病学研究。
地点:苏格兰人口。
参与者:苏格兰所有住院患者均按诊断编码。这些数据由信息服务部苏格兰收集(并从该部门获得)。那些在 2005 年至 2010 年间被编码为骨不连的患者被纳入研究。没有排除任何患者。人口数据来自苏格兰登记总干事。
观察指标:根据年龄、性别和不愈合的解剖分布,苏格兰每 10 万人中骨折不愈合的人数。
结果:2005 年至 2010 年间,苏格兰共有 4895 例不愈合患者住院治疗,平均每年 979 例,总发病率为每 10 万人每年 18.94 例。按性别分布,男性占 57%,女性占 43%。按年龄分布,总体发病高峰在 30 至 40 岁之间。2005 年至 2010 年期间,苏格兰的平均人口为 5169140 人。
结论:总体而言,整个人群的骨折不愈合率仍然较低,不到每 10 万人 20 例,在生命的第四个十年达到峰值。需要进一步研究以确定按年龄/性别/解剖分布每例骨折的不愈合风险。
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