Mücke Thomas, Loeffelbein Denys J, Kolk Andreas, Wagenpfeil Stefan, Kanatas Anastasios, Wolff Klaus-Dietrich, Mitchell David A, Kesting Marco R
Department of Oral and Maxillofacial Surgery, Technische Universität München, Klinikum Rechts der Isar, Germany.
Br J Oral Maxillofac Surg. 2013 Sep;51(6):514-9. doi: 10.1016/j.bjoms.2013.01.007. Epub 2013 Feb 8.
Several microvascular free flaps are available for reconstruction of the osseous components after resections for head and neck cancer. We have prospectively evaluated patients treated by bony microsurgical reconstruction to identify predictors of adverse outcomes for delayed wound healing and failure of free flaps. All patients from July 2007 to June 2011 who had reconstructions with microvascular fibular or iliac crest flaps immediately after resection of the tumour were evaluated. There were a total of 156 bony free flaps: 120 (77%) fibular and 36 (23%) iliac crest flaps. A total of 133 (85%) were successful. Delayed wound healing was more common with the iliac crest flap (p=0.01) at the intraoral site (p=0.04). Significantly more iliac crest free flaps failed (p=0.02). Anastomosis to the facial artery (p=0.05) and facial vein (p=0.04), and duration of overall operating time were associated with a significantly higher risk of failure of the flap. Patients with cancer of the head and neck who require microsurgical bony reconstruction are at increased risk of postoperative complications. Significantly more complications were found with the iliac crest flap, whereas the fibular flap was associated with a significantly longer operating time.
有几种微血管游离皮瓣可用于头颈部癌切除术后骨组织的重建。我们对接受骨显微外科重建治疗的患者进行了前瞻性评估,以确定延迟伤口愈合和游离皮瓣失败等不良结局的预测因素。对2007年7月至2011年6月期间所有在肿瘤切除后立即采用微血管腓骨或髂嵴皮瓣进行重建的患者进行了评估。共有156例骨游离皮瓣:120例(77%)为腓骨皮瓣,36例(23%)为髂嵴皮瓣。共有133例(85%)成功。在口内部位,髂嵴皮瓣延迟伤口愈合更为常见(p = 0.01)(p = 0.04)。髂嵴游离皮瓣失败的情况明显更多(p = 0.02)。与面动脉(p = 0.05)和面静脉(p = 0.04)吻合以及总手术时间与皮瓣失败风险显著升高相关。需要进行显微外科骨重建的头颈部癌患者术后并发症风险增加。髂嵴皮瓣出现的并发症明显更多,而腓骨皮瓣的手术时间明显更长。