1Department of Cardiology, Mustafa Kemal University Medical School, Hatay, Turkey.
Clin Appl Thromb Hemost. 2014 Jan;20(1):31-6. doi: 10.1177/1076029613476340. Epub 2013 Feb 12.
We aimed to investigate the association between electrocardiographic (ECG) grade III ischemia and angiographic thrombus burden in patients with acute ST-segment elevation myocardial infarction (STEMI) who underwent primary percutaneous coronary intervention (pPCI).
The study population consisted of 307 patients with STEMI. Baseline ECGs of the patients were analyzed for grade III ischemia; angiographic thrombus burden was assessed by thrombolysis in myocardial infarction thrombus classification.
A total of 108 (35%) patients had low thrombus burden whereas 199 (65%) patients had high thrombus burden. Grade III ischemia was more prevalent in patients with high thrombus burden (25.1% vs 11.1%, P = .004). Only grade III ischemia (odds ratio: 2.59, 95% confidence interval 1.24-5.39, P = .011) and history of coronary artery disease (CAD) were found to be the independent predictors of high thrombus burden.
Grade III ischemia on ECG and previous history of CAD were independent predictors of coronary thrombus burden in patients with STEMI who underwent pPCI.
我们旨在研究行直接经皮冠状动脉介入治疗（pPCI）的急性 ST 段抬高型心肌梗死（STEMI）患者心电图（ECG）III 级缺血与血管造影血栓负担之间的关联。
研究人群包括 307 例 STEMI 患者。分析患者的基线 ECG 是否存在 III 级缺血；通过心肌梗死溶栓治疗血栓分级评估血管造影血栓负担。
共有 108 例（35%）患者血栓负担低，199 例（65%）患者血栓负担高。高血栓负担患者中 III 级缺血更为常见（25.1% vs 11.1%，P =.004）。仅 III 级缺血（优势比：2.59，95%置信区间 1.24-5.39，P =.011）和冠心病（CAD）病史被认为是高血栓负担的独立预测因素。
在接受 pPCI 的 STEMI 患者中，ECG 上的 III 级缺血和既往 CAD 病史是冠状动脉血栓负担的独立预测因素。
Zotero 插件