Boston, Mass.; Toronto, Ontario, Canada; and Valencia, Spain From the Division of Plastic Surgery, Brigham and Women's Hospital; the Division of Plastic Surgery, Sick Kids Hospital; and Clinica Cavadas.
Plast Reconstr Surg. 2013 Jun;131(6):1272-1277. doi: 10.1097/PRS.0b013e31828bd1a5.
Despite generally excellent success with vascularized composite allotransplantation at many body sites over the past two decades, vascularized composite allotransplantation as a treatment modality for lower extremity amputees has not yet been fully embraced.
The authors summarize the anticipated benefits of lower limb allotransplantation, and reference the likely controversies relevant to this restorative therapeutic modality.
Based on evidence culled from both upper extremity and lower extremity transplant experience to date, the authors posit that allotransplantation for lower limb amputees may be a reasonable pursuit.
The authors advocate for the renewed consideration of lower extremity allotransplantation.
尽管在过去的二十年中,许多身体部位的血管化复合组织同种异体移植取得了优异的整体效果,但血管化复合组织同种异体移植作为下肢截肢患者的治疗方式尚未被完全接受。
作者总结了下肢同种异体移植的预期益处,并参考了与这种修复治疗模式相关的可能争议。
基于迄今为止从上肢和下肢移植经验中收集的证据,作者认为下肢截肢患者的同种异体移植可能是一种合理的选择。
作者主张重新考虑下肢同种异体移植。