[Cctionic selectivity of bimolecular membranes in the presence of nystatin and amphotericin B].

Ergosterin or 7-dehydrocholesterin-containing artificial membranes are selectively permeable for cations of alkaline metals in aqueous solutions of nistatin and amphotericine B. Membrane permeability changes spontaneously within several tens of minutes from the cation to the anion one. A decrease of temperature, an increase of medium pH or introduction of dimethylsulphoxide into aqueous solution inhibit, while the addition of calcium accelerate this transition.