El Maaroufi H, El Ouazzani Chahdi K, Doghmi K, Mikdame M
Service d'hématologie clinique, université Mohamed V-Souissi, hôpital militaire d'instruction Mohammed V, Hay Riad, 10100 Rabat, Maroc.
J Fr Ophtalmol. 2013 Apr;36(4):e55-7. doi: 10.1016/j.jfo.2012.06.024. Epub 2013 Feb 21.
Ophthalmological involvement in mantle cell lymphoma is rare. An 84-year-old man presented with bilateral proptosis. Orbital biopsy established the diagnosis of mantle cell lymphoma. The diagnosis of mantle cell lymphoma is anatomopathological and immuno-histochemical. Orbital involvement is found most often in advanced stages of the disease, but may be the presenting sign as in the case of our patient. Treatment has improved with the use of rituximab, especially in elderly patients not eligible for autologous hematopoietic stem cell transplant.
套细胞淋巴瘤累及眼部罕见。一名84岁男性出现双侧眼球突出。眼眶活检确诊为套细胞淋巴瘤。套细胞淋巴瘤的诊断依靠解剖病理学和免疫组织化学检查。眼眶受累最常出现在疾病晚期,但也可能像我们的患者这样是首发症状。使用利妥昔单抗后治疗效果有所改善,尤其对于不适合自体造血干细胞移植的老年患者。